Achievements and Prospects in Electrochemical-Based Biosensing Platforms for Aflatoxin M1 Detection in Milk and Dairy Products

被引:25
|
作者
Gurban, Ana-Maria [1 ]
Epure, Petru [2 ]
Oancea, Florin [1 ]
Doni, Mihaela [1 ]
机构
[1] Natl Inst Res & Dev Chem & Petrochem ICECHIM, Biotechnol Dept, 202 Spl Independentei,Sect 6, Bucharest 060021, Romania
[2] EPI SISTEM SRL, Blvd Brasovului 145, Sacele 505600, Brasov, Romania
关键词
aflatoxin M-1; immunoassays; antibody; aptamer; electrochemical biosensors; PERFORMANCE LIQUID-CHROMATOGRAPHY; THIN-LAYER-CHROMATOGRAPHY; RAW-MILK; BREAST-MILK; COW MILK; M1; DETERMINATION; RAPID DETECTION; SAMPLE CLEANUP; MYCOTOXINS; FLUORESCENCE;
D O I
10.3390/s17122951
中图分类号
O65 [分析化学];
学科分类号
070302 ; 081704 ;
摘要
Aflatoxins, which are mainly produced by Aspergillus flavus and parasiticus growing on plants and products stored under inappropriate conditions, represent the most studied group of mycotoxins. Contamination of human and animal milk with aflatoxin M-1, the hydroxylated metabolite of aflatoxin B-1, is an important health risk factor due to its carcinogenicity and mutagenicity. Due to the low concentration of this aflatoxin in milk and milk products, the analytical methods used for its quantification have to be highly sensitive, specific and simple. This paper presents an overview of the analytical methods, especially of the electrochemical immunosensors and aptasensors, used for determination of aflatoxin M-1.
引用
收藏
页数:21
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