EANM guidelines for radionuclide therapy of bone metastases with beta-emitting radionuclides

被引：46

作者：

Handkiewicz-Junak, Daria ^{[1
,2
]}

Poeppel, Thorsten D. ^{[3
]}

Bodei, Lisa ^{[4
]}

Aktolun, Cumali ^{[5
]}

Ezziddin, Samer ^{[6
]}

Giammarile, Francesco ^{[7
]}

Delgado-Bolton, Roberto C. ^{[8
,9
]}

Gabriel, Michael ^{[10
,11
]}

机构：

[1] Maria Sklodowska Curie Mem Canc Ctr, Nucl Med & Endocrine Oncol Dept, Gliwice, Poland

[2] Inst Oncol, Gliwice, Poland

[3] Univ Hosp Essen, Clin Nucl Med, Essen, Germany

[4] Mem Sloan Kettering Canc Ctr, Dept Radiol, 1275 York Ave, New York, NY 10021 USA

[5] Tiroctr Nucl Med Ctr, Istanbul, Turkey

[6] Saarland Univ, Univ Hosp USK, Nucl Med, Hamburg, Germany

[7] IAEA, Nucl Med & Diagnost Imaging Sect, Vienna, Austria

[8] Univ Hosp San Pedro, Dept Diagnost Imaging Radiol & Nucl Med, Logrono, La Rioja, Spain

[9] Ctr Biomed Res La Rioja, Logrono, La Rioja, Spain

[10] Kepler Univ Hosp, Inst Nucl Med & Endocrinol, Linz, Austria

[11] Med Univ Innsbruck, Univ Clin Nucl Med, Innsbruck, Austria

来源：

EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING | 2018年 / 45卷 / 05期

关键词：

Radionuclide therapy; Bone metastase; Beta-emitting radionuclides; Strontium-89; Samarium-153; Phosphorus-32; Efficacy; PAINFUL SKELETAL METASTASES; REFRACTORY PROSTATE-CANCER; BREAST-CANCER; PALLIATIVE TREATMENT; SR-89; THERAPY; PAMIDRONATE DISODIUM; OSSEOUS METASTASES; ZOLEDRONIC ACID; PLUS PREDNISONE; PHASE-III;

D O I：

10.1007/s00259-018-3947-x

中图分类号：

R8 [特种医学]; R445 [影像诊断学];

学科分类号：

1002 ; 100207 ; 1009 ;

摘要：

The skeleton is the most common metastatic site in patients with advanced cancer. Pain is a major healthcare problem in patients with bone metastases. Bone-seeking radionuclides that selectively accumulate in the bone are used to treat cancer-induced bone pain and to prolong survival in selected groups of cancer patients. The goals of these guidelines are to assist nuclear medicine practitioners in: (a) evaluating patients who might be candidates for radionuclide treatment of bone metastases using beta-emitting radionuclides such as strontium-89 (Sr-89), samarium-153 (Sm-153) lexidronam (Sm-153-EDTMP), and phosphorus-32 (P-32) sodium phosphate; (b) performing the treatments; and (c)) understanding and evaluating the treatment outcome and side effects.

引用

页码：846 / 859

页数：14

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