DEVELOPMENT-RELATED PcG TARGET IN THE APEX 4 controls leaf margin architecture in Arabidopsis thaliana

被引：32

作者：

Engelhorn, Julia ^{[1
]}

Reimer, Julia J. ^{[1
]}

Leuz, Iris ^{[1
]}

Goebel, Ulrike

Huettel, Bruno ^{[2
]}

Farrona, Sara ^{[1
]}

Turck, Franziska ^{[1
]}

机构：

[1] Max Planck Inst Plant Breeding Res, Dept Plant Dev Biol, D-50829 Cologne, Germany

[2] Max Planck Inst Plant Breeding Res, Max Planck Genome Ctr Cologne, D-50829 Cologne, Germany

来源：

DEVELOPMENT | 2012年 / 139卷 / 14期

关键词：

Leaf serration development; Polycomb group; Auxin; CUP-SHAPED COTYLEDON 2; Arabidopsis thaliana; FLOWERING-LOCUS-T; HYBRIDIZATION (CHIP-CHIP). PART; PROTEIN-DNA INTERACTION; SHAPED-COTYLEDON GENES; POLYCOMB-GROUP; CHROMATIN IMMUNOPRECIPITATION; EXPRESSION; EVOLUTION; TRANSCRIPTION; REPRESSION;

D O I：

10.1242/dev.078618

中图分类号：

Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

In a reverse genetics screen based on a group of genes enriched for development-related Polycomb group targets in the apex (DPAs), we isolated DPA4 as a novel regulator of leaf margin shape. T-DNA insertion lines in the DPA4 locus display enhanced leaf margin serrations and enlarged petals, whereas overexpression of DPA4 results in smooth margins. DPA4 encodes a putative RAV (Related to ABI3/VP1) transcriptional repressor and is expressed in the lateral organ boundary region and in the sinus of leaf serrations. DPA4 expression domains overlap with those of the known leaf shape regulator CUP-SHAPED COTYLEDON 2 (CUC2) and we provide evidence that DPA4 negatively regulates CUC2 expression independently of MIR164A, an established regulator of CUC2. Taken together, the data suggest DPA4 as a newly identified player in the signalling network that controls leaf serrations in Arabidopsis thaliana.

引用

页码：2566 / 2575

页数：10

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