Electromagnetic Detection of HIV DNA in the Blood of AIDS Patients Treated by Antiretroviral Therapy
被引:35
|
作者:
Montagnier, Luc
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机构:
World Fdn AIDS Res & Prevent UNESCO, F-75015 Paris, France
Nanectis Biotechnol, F-78350 Jouy En Josas, FranceWorld Fdn AIDS Res & Prevent UNESCO, F-75015 Paris, France
Montagnier, Luc
[1
,2
]
Aissa, Jamal
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机构:
Nanectis Biotechnol, F-78350 Jouy En Josas, FranceWorld Fdn AIDS Res & Prevent UNESCO, F-75015 Paris, France
Aissa, Jamal
[2
]
Lavallee, Claude
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机构:
World Fdn AIDS Res & Prevent UNESCO, F-75015 Paris, FranceWorld Fdn AIDS Res & Prevent UNESCO, F-75015 Paris, France
Lavallee, Claude
[1
]
Mbamy, Mireille
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机构:
CIRBA Ctr Integre Rech Bioclin Abidjan, Abidjan 18, Cote IvoireWorld Fdn AIDS Res & Prevent UNESCO, F-75015 Paris, France
Mbamy, Mireille
[3
]
Varon, Joseph
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机构:
Univ Texas Hlth Sci Ctr, Houston, TX 77030 USAWorld Fdn AIDS Res & Prevent UNESCO, F-75015 Paris, France
Varon, Joseph
[4
]
Chenal, Henri
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机构:
CIRBA Ctr Integre Rech Bioclin Abidjan, Abidjan 18, Cote IvoireWorld Fdn AIDS Res & Prevent UNESCO, F-75015 Paris, France
Chenal, Henri
[3
]
机构:
[1] World Fdn AIDS Res & Prevent UNESCO, F-75015 Paris, France
[2] Nanectis Biotechnol, F-78350 Jouy En Josas, France
HIV DNA;
antiretroviral therapy;
HIV reservoir;
HIV LTR detection;
HIV DNA with erythrocyte fraction;
D O I:
10.1007/s12539-009-0059-0
中图分类号:
Q [生物科学];
学科分类号:
07 ;
0710 ;
09 ;
摘要:
Electromagnetic signals of low frequency have been shown to be durably produced in aqueous dilutions of the Human Imunodeficiency Virus DNA. In vivo, HIV DNA signals are detected only in patients previously treated by antiretroviral therapy and having no detectable viral RNA copies in their blood. We suggest that the treatment of AIDS patients pushes the virus towards a new mode of replication implying only DNA, thus forming a reservoir insensitive to retroviral inhibitors. Implications for new approaches aimed at eradicating HIV infection are discussed.
机构:
Univ Toulouse 3, INSERM, Reg Ctr HIV Care & Coordinat, UMR1027, F-31062 Toulouse, FranceUniv Toulouse 3, INSERM, Reg Ctr HIV Care & Coordinat, UMR1027, F-31062 Toulouse, France
Cuzin, Lise
Pugliese, Pascal
论文数: 0引用数: 0
h-index: 0
机构:
CHU Archet, Dept Infect Dis, Nice, FranceUniv Toulouse 3, INSERM, Reg Ctr HIV Care & Coordinat, UMR1027, F-31062 Toulouse, France
Pugliese, Pascal
Saune, Karine
论文数: 0引用数: 0
h-index: 0
机构:
Ctr Physiopathol Toulouse Purpan, INSERM, U1043, Toulouse, France
CHU Toulouse, Hop Purpan, Dept Virol, Natl Reference Ctr Hepatitis E,Inst Federatif Bio, Toulouse, FranceUniv Toulouse 3, INSERM, Reg Ctr HIV Care & Coordinat, UMR1027, F-31062 Toulouse, France
Saune, Karine
Allavena, Clotilde
论文数: 0引用数: 0
h-index: 0
机构:
CHU Hotel Dieu, Dept Infect Dis, Nantes, FranceUniv Toulouse 3, INSERM, Reg Ctr HIV Care & Coordinat, UMR1027, F-31062 Toulouse, France
Allavena, Clotilde
Ghosn, Jade
论文数: 0引用数: 0
h-index: 0
机构:
Hop Hotel Dieu, AP HP, Dept Therapeut Infect Dis, Paris, France
Paris Descartes Univ, Sorbonne Paris Cite, EA 7327, Paris, FranceUniv Toulouse 3, INSERM, Reg Ctr HIV Care & Coordinat, UMR1027, F-31062 Toulouse, France
Ghosn, Jade
Cottalorda, Jacqueline
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h-index: 0
机构:
CHU Nice, Dept Virol, F-06202 Nice, FranceUniv Toulouse 3, INSERM, Reg Ctr HIV Care & Coordinat, UMR1027, F-31062 Toulouse, France
Cottalorda, Jacqueline
Rodallec, Audrey
论文数: 0引用数: 0
h-index: 0
机构:
CHU Nantes, Dept Virol, F-44035 Nantes 01, FranceUniv Toulouse 3, INSERM, Reg Ctr HIV Care & Coordinat, UMR1027, F-31062 Toulouse, France
Rodallec, Audrey
Chaix, Marie Laure
论文数: 0引用数: 0
h-index: 0
机构:
Paris Diderot Univ, Hop St Louis, AP HP, Virol Dept,INSERM,U941, Paris, FranceUniv Toulouse 3, INSERM, Reg Ctr HIV Care & Coordinat, UMR1027, F-31062 Toulouse, France
Chaix, Marie Laure
Fafi-Kremer, Samira
论文数: 0引用数: 0
h-index: 0
机构:
CHU Strasbourg, Dept Virol, F-67000 Strasbourg, FranceUniv Toulouse 3, INSERM, Reg Ctr HIV Care & Coordinat, UMR1027, F-31062 Toulouse, France
Fafi-Kremer, Samira
Soulie, Cathia
论文数: 0引用数: 0
h-index: 0
机构:
Univ Paris 06, Univ Paris 04, Pierre Louis Inst Epidemiol & Publ Hlth, UMR S 1136, Paris, France
Pierre Louis Inst Epidemiol & Publ Hlth, INSERM, UMR S 1136, Paris, France
Grp Hosp Pitie Salpetriere, AP HP, Virol Lab, F-75634 Paris, FranceUniv Toulouse 3, INSERM, Reg Ctr HIV Care & Coordinat, UMR1027, F-31062 Toulouse, France
Soulie, Cathia
Ouka, Marlene
论文数: 0引用数: 0
h-index: 0
机构:
Univ Hosp Martinique, Virol Lab, Fort De France, FranceUniv Toulouse 3, INSERM, Reg Ctr HIV Care & Coordinat, UMR1027, F-31062 Toulouse, France
Ouka, Marlene
Charpentier, Charlotte
论文数: 0引用数: 0
h-index: 0
机构:
INSERM, IAME, UMR 1137, Paris, France
Univ Paris Diderot, Sorbonne Paris Cite, IAME, UMR 1137, Paris, France
Hop Bichat Claude Bernard, AP HP, Dept Virol, F-75877 Paris 18, FranceUniv Toulouse 3, INSERM, Reg Ctr HIV Care & Coordinat, UMR1027, F-31062 Toulouse, France
Charpentier, Charlotte
Bocket, Laurence
论文数: 0引用数: 0
h-index: 0
机构:
CHU Lille, Dept Virol, F-59037 Lille, FranceUniv Toulouse 3, INSERM, Reg Ctr HIV Care & Coordinat, UMR1027, F-31062 Toulouse, France
Bocket, Laurence
Mirand, Audrey
论文数: 0引用数: 0
h-index: 0
机构:
CHU Clermont Ferrand, Hop Gabriel Montpied, Virol Lab, Clermont Ferrand, FranceUniv Toulouse 3, INSERM, Reg Ctr HIV Care & Coordinat, UMR1027, F-31062 Toulouse, France
Mirand, Audrey
Guiguet, Marguerite
论文数: 0引用数: 0
h-index: 0
机构:
Univ Paris 06, Univ Paris 04, INSERM, UMR S 1136,Pierre Louis Inst Epidemiol & Publ Hlt, Paris, FranceUniv Toulouse 3, INSERM, Reg Ctr HIV Care & Coordinat, UMR1027, F-31062 Toulouse, France
机构:
Univ Calif Los Angeles, Semel Inst, Ctr Community Hlth, Los Angeles, CA 90024 USAUniv Calif Los Angeles, Semel Inst, Ctr Community Hlth, Los Angeles, CA 90024 USA
Li, Li
Lee, Sung-Jae
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机构:
Univ Calif Los Angeles, Semel Inst, Ctr Community Hlth, Los Angeles, CA 90024 USAUniv Calif Los Angeles, Semel Inst, Ctr Community Hlth, Los Angeles, CA 90024 USA
Lee, Sung-Jae
Wen, Yi
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机构:
Univ Calif Los Angeles, Semel Inst, Ctr Community Hlth, Los Angeles, CA 90024 USAUniv Calif Los Angeles, Semel Inst, Ctr Community Hlth, Los Angeles, CA 90024 USA
Wen, Yi
Lin, Chunqing
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机构:
Univ Calif Los Angeles, Semel Inst, Ctr Community Hlth, Los Angeles, CA 90024 USAUniv Calif Los Angeles, Semel Inst, Ctr Community Hlth, Los Angeles, CA 90024 USA
Lin, Chunqing
Wan, Dai
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机构:
Univ Calif Los Angeles, Semel Inst, Ctr Community Hlth, Los Angeles, CA 90024 USAUniv Calif Los Angeles, Semel Inst, Ctr Community Hlth, Los Angeles, CA 90024 USA
Wan, Dai
Jiraphongsa, Chuleeporn
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机构:
Minist Publ Hlth, Bur Epidemiol, Bangkok, ThailandUniv Calif Los Angeles, Semel Inst, Ctr Community Hlth, Los Angeles, CA 90024 USA
机构:
Gandaki Med Coll & Teaching Hosp, Dept Gen Practice & Emergency Med, Pokhara, NepalGandaki Med Coll & Teaching Hosp, Dept Gen Practice & Emergency Med, Pokhara, Nepal
Gupta, Sandeep
Gupta, Chandan Kumar
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机构:
Murarilal Gupta Mem Hosp, Salampur, UP, IndiaGandaki Med Coll & Teaching Hosp, Dept Gen Practice & Emergency Med, Pokhara, Nepal
Gupta, Chandan Kumar
Shyam, B. K.
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机构:
Nepalgunj Med Coll & Teaching Hosp, Dept Internal Med, Nepalganj, NepalGandaki Med Coll & Teaching Hosp, Dept Gen Practice & Emergency Med, Pokhara, Nepal
Shyam, B. K.
Gupta, Nupur
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机构:
Pokhara Univ, Sch Dev & Social Engn, Kaski, NepalGandaki Med Coll & Teaching Hosp, Dept Gen Practice & Emergency Med, Pokhara, Nepal
机构:
Hosp Enfermedades Infecciosas Francisco J Muniz, Buenos Aires, DF, ArgentinaHosp Enfermedades Infecciosas Francisco J Muniz, Buenos Aires, DF, Argentina
Waisman, JL
Palmero, DJ
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h-index: 0
机构:
Hosp Enfermedades Infecciosas Francisco J Muniz, Buenos Aires, DF, ArgentinaHosp Enfermedades Infecciosas Francisco J Muniz, Buenos Aires, DF, Argentina
Palmero, DJ
Alberti, FA
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h-index: 0
机构:
Hosp Enfermedades Infecciosas Francisco J Muniz, Buenos Aires, DF, ArgentinaHosp Enfermedades Infecciosas Francisco J Muniz, Buenos Aires, DF, Argentina
Alberti, FA
Gurtubay, JLG
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h-index: 0
机构:
Hosp Enfermedades Infecciosas Francisco J Muniz, Buenos Aires, DF, ArgentinaHosp Enfermedades Infecciosas Francisco J Muniz, Buenos Aires, DF, Argentina
Gurtubay, JLG
Francos, JL
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Hosp Enfermedades Infecciosas Francisco J Muniz, Buenos Aires, DF, ArgentinaHosp Enfermedades Infecciosas Francisco J Muniz, Buenos Aires, DF, Argentina
Francos, JL
Negroni, R
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Hosp Enfermedades Infecciosas Francisco J Muniz, Buenos Aires, DF, ArgentinaHosp Enfermedades Infecciosas Francisco J Muniz, Buenos Aires, DF, Argentina