A Comprehensive Approach to Pouch Disorders

被引:33
|
作者
Quinn, Kevin P. [1 ]
Lightner, Amy L. [2 ]
Faubion, William A. [1 ]
Raffals, Laura E. [1 ]
机构
[1] Mayo Clin, Div Gastroenterol & Hepatol, Rochester, MN USA
[2] Mayo Clin, Div Colon & Rectal Surg, Rochester, MN USA
关键词
ileal pouch-anal anastomosis; pouch dysfunction; pouchitis; FAMILIAL ADENOMATOUS POLYPOSIS; CLOSTRIDIUM-DIFFICILE INFECTION; LONG-TERM OUTCOMES; QUALITY-OF-LIFE; ILEAL POUCH; ANAL ANASTOMOSIS; RESTORATIVE PROCTOCOLECTOMY; CROHNS-DISEASE; ULCERATIVE-COLITIS; DOUBLE-BLIND;
D O I
10.1093/ibd/izy267
中图分类号
R57 [消化系及腹部疾病];
学科分类号
摘要
Restorative proctocolectomy with ileal pouch-anal anastomosis (IPAA) is the surgical procedure of choice for patients with medically refractory ulcerative colitis (UC) or indeterminate colitis, UC with colonic dysplasia or neoplasia, and familial adenomatous polyposis. In general, patients experience good function outcomes and quality of life with an IPAA. Although pouchitis is the most well-recognized and frequent complication after IPAA, a number of additional inflammatory, postsurgical, structural, neoplastic, and functional complications may occur, resulting in pouch dysfunction. We herein provide a comprehensive review of pouch function and an approach to diagnosis and management of pouch complications.
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页码:460 / 471
页数:12
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