THE PREVALENCE OF POTENTIAL DRUG-DRUG INTERACTIONS IN THE THERAPY OF ROMANIAN COMMUNITY PHARMACY'S PATIENTS

被引：0
|
作者：
Bucsa, Camelia Denisa [1 ]
Cazacu, Irina [1 ]
Farcas, Andreea Maria [1 ]
机构：
[1] Univ Med & Pharm Iuliu Hatieganu, Drug Informat Res Ctr, Fac Pharm, Cluj Napoca, Romania
来源：
FARMACIA | 2012年 / 60卷 / 04期
关键词：
drug-drug interactions; adverse drug reactions; community pharmacy; HOSPITAL ADMISSIONS; ADVERSE; MEDICINE;
D O I：
暂无
中图分类号：
R9 [药学];
学科分类号：
1007 ;
摘要：
Drug-drug interactions (DDIs) are a concern for patients and providers, as multiple medication use is becoming more common to manage complex diseases. However, a high prevalence of potential drug-drug interactions (pDDIs) can lead to a higher probability to develop an adverse drug reaction (ADR) or suboptimal therapeutic effects. The objective of our study was to measure the frequency, nature and severity of the potential DDIs in prescriptions from a Romanian community pharmacy. We analysed 308 prescriptions (all reimbursed prescriptions from one month) of 243 patients for the detection of the pDDIs. Our study showed that potential drug-drug interactions are highly prevalent (34.42% of prescriptions with at least one DDI) in patients' therapy and the modernization of prescribing and dispensing medicines is necessary.
引用
收藏
页码：510 / 516
页数：7
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