One-Pot Access to Cinnamates via Direct Oxidative C-H Transformation of Allylarenes

被引：10

作者：

Chang, Meng-Yang ^{[1
]}

Lin, Shin-Ying ^{[1
]}

Chan, Chieh-Kai ^{[1
]}

机构：

[1] Kaohsiung Med Univ, Dept Med & Appl Chem, Kaohsiung 807, Taiwan

来源：

SYNLETT | 2013年 / 24卷 / 04期

关键词：

allylarenes; C-H esterification; cinnamates; ALLYLIC OXIDATION; BOND FUNCTIONALIZATION; DDQ; AMINATION; CYCLIZATION; ACTIVATION; ALCOHOLS; ALKENES; ESTERS; CINNAMALDEHYDES;

D O I：

10.1055/s-0032-1318146

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A highly selective combination of ruthenium complex and oxidant, which catalyzes the oxidative C-H esterification of allylarenes to the corresponding bis-(E)-cinnamates and (E)-cinnamates, is described. The one-pot route was carried out by olefinic migration of allylarenes with RuCl2(PPh3)(3) and DDQ-mediated allylic oxidation of the resulting internal alkenes with various alcohols in good yields.

引用

页码：487 / 490

页数：4

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