Priority-setting for obesity prevention-The Assessing Cost-Effectiveness of obesity prevention policies in Australia (ACE-Obesity Policy) study

被引:61
作者
Ananthapavan, Jaithri [1 ,2 ]
Sacks, Gary [2 ]
Brown, Vicki [1 ,2 ]
Moodie, Marj [1 ,2 ]
Nguyen, Phuong [1 ,2 ]
Veerman, Lennert [3 ]
Herrera, Ana Maria Mantilla [4 ,5 ,6 ]
Lal, Anita [1 ,2 ]
Peeters, Anna [2 ]
Carter, Rob [1 ]
机构
[1] Deakin Univ, Sch Hlth & Social Dev, Inst Hlth Transformat, Deakin Hlth Econ, Geelong, Vic, Australia
[2] Deakin Univ, Global Obes Ctr, Sch Hlth & Social Dev, Inst Hlth Transformat, Geelong, Vic, Australia
[3] Griffith Univ, Sch Med, Gold Coast, Australia
[4] Queensland Ctr Mental Hlth Res, Brisbane, Qld, Australia
[5] Univ Queensland, Sch Publ Hlth, Brisbane, Qld, Australia
[6] Univ Washington, Inst Hlth Metr & Evaluat, Seattle, WA 98195 USA
基金
澳大利亚研究理事会; 英国医学研究理事会;
关键词
INTERVENTIONS; ADOLESCENTS; CHILDREN; LIFE;
D O I
10.1371/journal.pone.0234804
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
The aim of the ACE-Obesity Policy study was to assess the economic credentials of a suite of obesity prevention policies across multiple sectors and areas of governance for the Australian setting. The study aimed to place the cost-effectiveness results within a broad decision-making context by providing an assessment of the key considerations for policy implementation. The Assessing Cost-Effectiveness (ACE) approach to priority-setting was used. Systematic literature reviews were undertaken to assess the evidence of intervention effectiveness on body mass index and/or physical activity for selected interventions. A standardised evaluation framework was used to assess the cost-effectiveness of each intervention compared to a 'no intervention' comparator, from a limited societal perspective. A multi-state life table Markov cohort model was used to estimate the long-term health impacts (quantified as health adjusted life years (HALYs)) and health care cost-savings resulting from each intervention. In addition to the technical cost-effectiveness results, qualitative assessments of implementation considerations were undertaken. All 16 interventions evaluated were found to be cost-effective (using a willingness-to-pay threshold of AUD50,000 per HALY gained). Eleven interventions were dominant (health promoting and cost-saving). The incremental cost-effectiveness ratio for the non-dominant interventions ranged from AUD1,728 to 28,703 per HALY gained. Regulatory interventions tended to rank higher on their cost-effectiveness results, driven by lower implementation costs. However, the program-based policy interventions were generally based on higher quality evidence of intervention effectiveness. This comparative analysis of the economic credentials of obesity prevention policies for Australia indicates that there are a broad range of policies that are likely to be cost-effective, although policy options vary in strength of evidence for effectiveness, affordability, feasibility, acceptability to stakeholders, equity impact and sustainability. Implementation of these policies will require sustained co-ordination across jurisdictions and multiple government sectors in order to generate the predicted health benefits for the Australian population.
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页数:19
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