Direct and short-time uptake of [70]fullerene into the cell membrane using an exchange reaction from a [70]fullerene-γ-cyclodextrin complex and the resulting photodynamic activity

被引:39
作者
Ikeda, Atsushi [1 ]
Matsumoto, Masashi [1 ]
Akiyama, Motofusa [1 ]
Kikuchi, Jun-ichi [1 ]
Ogawa, Takuya [2 ]
Takeya, Tatsuo [2 ]
机构
[1] Nara Inst Sci & Technol, Grad Sch Mat Sci, Ikoma 6300192, Japan
[2] Nara Inst Sci & Technol, Grad Sch Biol Sci, Ikoma 6300192, Japan
基金
日本学术振兴会;
关键词
THERAPY; SOLUBILIZATION; PHOTOCLEAVAGE; LIPOSOMES;
D O I
10.1039/b820768b
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
[70]Fullerene (C-70) was directly incorporated into the cell membrane using an exchange reaction from a C-70-gamma-cyclodextrin (gamma-CDx) complex within 10 min and the incorporated C-70 acted as a photodynamic sensitiser for a cancer cell.
引用
收藏
页码:1547 / 1549
页数:3
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