Spray-on-skin cells in burns: A common practice with no agreed protocol

被引:9
作者
Allouni, Ammar [1 ]
Papini, Remo [1 ]
Lewis, Darren [1 ]
机构
[1] Queen Elizabeth Hosp, Burns & Plast Dept, Birmingham B15 2TH, W Midlands, England
关键词
Burn; Spray; Cells; Cultured epithelial autograft; CULTURED EPITHELIAL AUTOGRAFTS;
D O I
10.1016/j.burns.2013.03.017
中图分类号
R4 [临床医学];
学科分类号
1002 ; 100602 ;
摘要
Objectives: Cultured epithelial autograft (CEA) has been used for skin coverage after burn wound excision since 1981. It is used in burn units and centres throughout the UK; however, there appears to be no agreed standards of practice. We aimed to investigate the experience and current practice with its usage in the management of acute burn injury. Methods: An online survey was sent to twenty-five burns consultants in the UK, who are members of the British Burn Association. Results: We received 14 responses. Rarely have the responders agreed to the same practice in most of the questions. Different choices were given by responders with regards the indications for cell culture, techniques used, primary and secondary dressings used, first wound review timing, and measures used to evaluate outcomes. Conclusion: In the current economic environment, the NHS needs to rationalize services on the basis of cost effectiveness. CEA is an expensive procedure that requires an adequately sterile laboratory, special equipments and highly experienced dedicated staff. When dealing with expensive management options, it is important to have an agreed protocol that can form the standard that can be referred to when auditing practices and results to improve burn management and patients' care. Crown Copyright (C) 2013 Published by Elsevier Ltd and ISBI. All rights reserved.
引用
收藏
页码:1391 / 1394
页数:4
相关论文
共 11 条
  • [1] Cultured epithelial autografts in massive burns: A single-center retrospective study with 63 patients
    Cirodde, Audrey
    Leclerc, Thomas
    Jault, Patrick
    Duhamel, Patrick
    Lataillade, Jean-Jacques
    Bargues, Laurent
    [J]. BURNS, 2011, 37 (06) : 964 - 972
  • [2] GREEN H, 1991, Scientific American, V265, P96
  • [3] Haberzeth SB, 2011, BURNS, V36, P450
  • [4] LEIGH IM, 1994, KERATINOCYTE HDB, P503
  • [5] Artificial skin, split-thickness autograft and cultured autologous keratinocytes combined to treat a severe burn injury of 93% of TBSA
    Loss, M
    Wedler, V
    Künzi, W
    Meuli-Simmen, C
    Meyer, VE
    [J]. BURNS, 2000, 26 (07) : 644 - 652
  • [6] Sprayed keratinocyte suspensions accelerate epidermal coverage in a porcine microwound model
    Navarro, FA
    Stoner, ML
    Park, CS
    Huertas, JC
    Lee, HB
    Wood, FM
    Orgill, DP
    [J]. JOURNAL OF BURN CARE & REHABILITATION, 2000, 21 (06): : 513 - 518
  • [7] OCONNOR NE, 1981, LANCET, V1, P75
  • [8] ODESSEY R, 1992, Journal of Burn Care and Rehabilitation, V13, P174, DOI 10.1097/00004630-199201000-00038
  • [9] The use of cultured epithelial autograft in the treatment of major burn injuries: A critical review of the literature
    Wood, F. M.
    Kolybaba, M. L.
    Allen, P.
    [J]. BURNS, 2006, 32 (04) : 395 - 401
  • [10] The use of cultured epithelial autograft in the treatment of major burn wounds: Eleven years of clinical experience
    Wood, F. M.
    Kolybaba, M. L.
    Allen, P.
    [J]. BURNS, 2006, 32 (05) : 538 - 544