INACTIVATION OF CYCLIN E1 ACTS PRO-APOPTOTIC AND ANTI-PROLIFERATIVE IN PRIMARY HEPATOMA CELLS AND PROTECTS FROM HEPATOCARCINOGENESIS IN MICE

被引：1
|
作者：
Sonntag, R. [1 ]
Moro, N. [2 ]
Nevzorova, Y. A. [1 ]
Bangen, J. M. [1 ]
Fahrenkamp, D. [3 ]
Lambertz, D. [1 ]
Hu, W. [1 ]
Gassler, N. [4 ]
Mueller-Newen, G. [3 ]
Weiskirchen, R. [5 ]
Barbacid, M. [6 ]
Sicinski, P. [7 ]
Trautwein, C. [1 ]
Liedtke, C. [1 ]
机构：
[1] Rhein Westfal TH Aachen, Dept Internal Med 3, Aachen, Germany
[2] Univ Hosp Koln, Dept Dermatol, Cologne, Germany
[3] Rhein Westfal TH Aachen, Inst Biochem & Mol Biol, Aachen, Germany
[4] Rhein Westfal TH Aachen, Inst Pathol, Aachen, Germany
[5] Rhein Westfal TH Aachen, Inst Mol Pathobiochem Expt Gene Therapy & Clin Ch, Aachen, Germany
[6] CNIO, Madrid, Spain
[7] Dana Farber Canc Inst, Dept Canc Biol, Boston, MA 02115 USA
来源：
JOURNAL OF HEPATOLOGY | 2015年 / 62卷
关键词：
D O I：
10.1016/S0168-8278(15)30501-8
中图分类号：
R57 [消化系及腹部疾病];
学科分类号：
摘要：
P0285
引用
收藏
页码：S414 / S415
页数：2
相关论文
共 50 条
  • [31] Anti-proliferative and pro-apoptotic activities of hydroxytyrosol on different tumour cells: the role of extracellular production of hydrogen peroxide
    Roberto Fabiani
    Maria Vittoria Sepporta
    Patrizia Rosignoli
    Angelo De Bartolomeo
    Marilena Crescimanno
    Guido Morozzi
    European Journal of Nutrition, 2012, 51 : 455 - 464
  • [32] High Glucose Represses the Anti-Proliferative and Pro-Apoptotic Effect of Metformin in Triple Negative Breast Cancer Cells
    Varghese, Sharon
    Samuel, Samson Mathews
    Varghese, Elizabeth
    Kubatka, Peter
    Busselberg, Dietrich
    BIOMOLECULES, 2019, 9 (01):
  • [33] Anti-proliferative and Pro-apoptotic Effects from Sequenced Combinations of Andrographolide and Cisplatin on Ovarian Cancer Cell Lines
    Yunos, Nurhanan M.
    Mutalip, Siti S. M.
    Jauri, Muhammad H.
    Yu, Jun Q.
    Huq, Fazlul
    ANTICANCER RESEARCH, 2013, 33 (10) : 4365 - 4371
  • [34] Anti-Proliferative and Pro-Apoptotic Activities of 4-Methyl-2,6-bis(1-phenylethyl)phenol in Cancer Cells
    Sung, Nak Yoon
    Kim, Seung Cheol
    Kim, Yun Hwan
    Kim, Gihyeon
    Lee, Yunmi
    Sung, Gi-Ho
    Kim, Ji Hye
    Yang, Woo Seok
    Kim, Mi Seon
    Baek, Kwang-Soo
    Kim, Jong-Hoon
    Choi, Jae Youl
    BIOMOLECULES & THERAPEUTICS, 2016, 24 (04) : 402 - 409
  • [35] Anti-proliferative and pro-apoptotic effects of imatinib on pulmonary artery smooth muscle cells from patients with idiopathic pulmonary arterial hypertension
    Nakamura, Kazufumi
    Akagi, Satoshi
    Ito, Hiroshi
    JOURNAL OF PHARMACOLOGICAL SCIENCES, 2013, 121 : 37P - 37P
  • [36] Novel combination of sorafenib and biochanin-A synergistically enhances the anti-proliferative and pro-apoptotic effects on hepatocellular carcinoma cells
    Youssef, Mohieldin M.
    Tolba, Mai F.
    Badawy, Noha N.
    Liu, Andrew W.
    El-Ahwany, Eman
    Khalifa, Amani E.
    Zada, Suher
    Abdel-Naim, Ashraf B.
    SCIENTIFIC REPORTS, 2016, 6
  • [37] Mechanisms of the anti-proliferative and pro-apoptotic effect of the herbal fixed combination STW 5 on colon adenocarcinoma cells in vitro
    Bonaterra, G.
    Kelber, O.
    Weiser, D.
    Okpanyi, S.
    Zuegel, S.
    Hildebrand, W.
    Kinscherf, R.
    PLANTA MEDICA, 2010, 76 (12) : 1190 - 1190
  • [38] Novel combination of salinomycin and resveratrol synergistically enhances the anti-proliferative and pro-apoptotic effects on human breast cancer cells
    Dewangan, Jayant
    Tandon, Divya
    Srivastava, Sonal
    Verma, Ajeet Kumar
    Yapuri, Ashok
    Rath, Srikanta Kumar
    APOPTOSIS, 2017, 22 (10) : 1246 - 1259
  • [39] Novel combination of sorafenib and biochanin-A synergistically enhances the anti-proliferative and pro-apoptotic effects on hepatocellular carcinoma cells
    Mohieldin M. Youssef 
    Mai F. Tolba
    Noha N. Badawy
    Andrew W. Liu
    Eman El-Ahwany
    Amani E. Khalifa
    Suher Zada
    Ashraf B. Abdel-Naim
    Scientific Reports, 6
  • [40] Kefir exhibits anti-proliferative and pro-apoptotic effects on colon adenocarcinoma cells with no significant effects on cell migration and invasion
    Khoury, Nathalie
    El-Hayek, Stephany
    Tarras, Omayr
    El-Sabban, Marwan
    El-Sibai, Mirvat
    Rizk, Sandra
    INTERNATIONAL JOURNAL OF ONCOLOGY, 2014, 45 (05) : 2117 - 2127
12345