Niches for Hematopoietic Stem Cells and Their Progeny

被引：298

作者：

Wei, Qiaozhi ^{[1
,2
]}

Frenette, Paul S. ^{[1
,2
,3
]}

机构：

[1] Albert Einstein Coll Med, Ruth L & David S Gottesman Inst Stem Cell & Regen, Bronx, NY 10461 USA

[2] Albert Einstein Coll Med, Dept Cell Biol, Bronx, NY 10461 USA

[3] Albert Einstein Coll Med, Dept Med, Bronx, NY 10461 USA

来源：

IMMUNITY | 2018年 / 48卷 / 04期

基金：

美国国家卫生研究院;

关键词：

COLONY-STIMULATING FACTOR; BONE-MARROW ADIPOCYTES; MESENCHYMAL STROMAL CELLS; CHEMOKINE RECEPTOR CXCR4; REGULATORY T-CELLS; NF-KAPPA-B; SELF-RENEWAL; ENDOTHELIAL-CELLS; EXTRAMEDULLARY HEMATOPOIESIS; LYMPHOID PROGENITORS;

D O I：

10.1016/j.immuni.2018.03.024

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Steady-state hematopoietic stem cells' (HSCs) self-renewal and differentiation toward their mature progeny in the adult bone marrow is tightly regulated by cues from the microenvironment. Recent insights into the cellular and molecular constituents have uncovered a high level of complexity. Here, we review emerging evidence showing how HSCs and their progeny are regulated by an interdependent network of mesenchymal stromal cells, nerve fibers, the vasculature, and also other hematopoietic cells. Understanding the interaction mechanisms in these intricate niches will provide great opportunities for HSC-related therapies and immune modulation.

引用

页码：632 / 648

页数：17

共 217 条

[1] Deep imaging of bone marrow shows non-dividing stem cells are mainly perisinusoidal [J].

Acar, Melih ;

Kocherlakota, Kiranmai S. ;

Murphy, Malea M. ;

Peyer, James G. ;

Oguro, Hideyuki ;

Inra, Christopher N. ;

Jaiyeola, Christabel ;

Zhao, Zhiyu ;

Luby-Phelps, Katherine ;

Morrison, Sean J. .

NATURE, 2015, 526 (7571) :126-+

[2] Identification of Flt3+ lympho-myeloid stem cells lacking erythro-megakaryocytic potential:: A revised road map for adult blood lineage commitment [J].

Adolfsson, J ;

Månsson, R ;

Buza-Vidas, N ;

Hultquist, A ;

Liuba, K ;

Jensen, CT ;

Bryder, D ;

Yang, LP ;

Borge, OJ ;

Thoren, LAM ;

Anderson, K ;

Sitnicka, E ;

Sasaki, Y ;

Sigvardsson, M ;

Jacobsen, SEW .

CELL, 2005, 121 (02) :295-306

[3] A clonogenic common myeloid progenitor that gives rise to all myeloid lineages [J].

Akashi, K ;

Traver, D ;

Miyamoto, T ;

Weissman, IL .

NATURE, 2000, 404 (6774) :193-197

[4] Bone Marrow Macrophages Contribute to Diabetic Stem Cell Mobilopathy by Producing Oncostatin M [J].

Albiero, Mattia ;

Poncina, Nicol ;

Ciciliot, Stefano ;

Cappellari, Roberta ;

Menegazzo, Lisa ;

Ferraro, Francesca ;

Bolego, Chiara ;

Cignarella, Andrea ;

Avogaro, Angelo ;

Fadini, Gian Paolo .

DIABETES, 2015, 64 (08) :2957-2968

[5] Memory CD8+ T cells colocalize with IL-7+ stromal cells in bone marrow and rest in terms of proliferation and transcription [J].

Alp, Oezen Sercan ;

Durlanik, Sibel ;

Schulz, Daniel ;

McGrath, Mairi ;

Gruen, Joachim R. ;

Bardua, Marcus ;

Ikuta, Koichi ;

Sgouroudis, Evridiki ;

Riedel, Rene ;

Zehentmeier, Sandra ;

Hauser, Anja E. ;

Tsuneto, Motokazu ;

Melchers, Fritz ;

Tokoyoda, Koji ;

Chang, Hyun-Dong ;

Thiel, Andreas ;

Radbruch, Andreas .

EUROPEAN JOURNAL OF IMMUNOLOGY, 2015, 45 (04) :975-987

[6] Adipocyte Accumulation in the Bone Marrow during Obesity and Aging Impairs Stem Cell-Based Hematopoietic and Bone Regeneration [J].

Ambrosi, Thomas H. ;

Scialdone, Antonio ;

Graja, Antonia ;

Gohlke, Sabrina ;

Jank, Anne-Marie ;

Bocian, Carla ;

Woelk, Lena ;

Fan, Hua ;

Logan, Darren W. ;

Schuermann, Annette ;

Saraiva, Luis R. ;

Schulz, Tim J. .

CELL STEM CELL, 2017, 20 (06) :771-+

[7] Neutrophils in Homeostasis, Immunity, and Cancer [J].

Angel Nicolas-Avila, Jose ;

Adrover, Jose M. ;

Hidalgo, Andres .

IMMUNITY, 2017, 46 (01) :15-28

[8] Differential cytokine contributions of perivascular haematopoietic stern cell niches [J].

Asada, Noboru ;

Kunisaki, Yuya ;

Pierce, Halley ;

Wang, Zichen ;

Fernandez, Nicolas F. ;

Birbrair, Alexander ;

Ma'ayan, Avi ;

Frenette, Paul S. .

NATURE CELL BIOLOGY, 2017, 19 (03) :214-223

[9] Matrix-Embedded Osteocytes Regulate Mobilization of Hematopoietic Stem/Progenitor Cells [J].

Asada, Noboru ;

Katayama, Yoshio ;

Sato, Mari ;

Minagawa, Kentaro ;

Wakahashi, Kanako ;

Kawano, Hiroki ;

Kawano, Yuko ;

Sada, Akiko ;

Ikeda, Kyoji ;

Matsui, Toshimitsu ;

Tanimoto, Mitsune .

CELL STEM CELL, 2013, 12 (06) :737-747

[10] Chemokine-mediated interaction of hematopoietic progenitors with the bone marrow vascular niche is required for thrombopoiesis [J].

Avecilla, ST ;

Hattori, K ;

Heissig, B ;

Tejada, R ;

Liao, F ;

Shido, K ;

Jin, DK ;

Dias, S ;

Zhang, F ;

Hartman, TE ;

Hackett, NR ;

Crystal, RG ;

Witte, L ;

Hicklin, DJ ;

Bohlen, P ;

Eaton, D ;

Lyden, D ;

de Sauvage, F ;

Rafii, S .

NATURE MEDICINE, 2004, 10 (01) :64-71

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