Development of a Chemically Crosslinked Poly(vinyl alcohol) Hydrogel for Injectable Nucleus Pulposus Replacement

被引:0
|
作者
Binetti, V. R. [1 ]
Marcolongo, M. [1 ]
Lowman, A. M. [2 ]
机构
[1] Drexel Univ, Mat Sci & Engn, Philadelphia, PA 19104 USA
[2] Temple Univ, Dept Bioengn, Philadelphia, PA 19122 USA
基金
美国国家科学基金会;
关键词
D O I
暂无
中图分类号
R318 [生物医学工程];
学科分类号
0831 ;
摘要
Poly(vinyl alcohol) (PVA) hydrogels have been chemically crosslinked using poly(ethylene glycol) diglycidyl ether (PEG-DGE) to develop a material for injectable nucleus pulposus replacement. The effects of PVA and PEG-DGE concentrations on compressive modulus and swelling have been deteremined in addition to the cytotoxic effects of crosslinking PVA with PEG-DGE.
引用
收藏
页码:378 / +
页数:2
相关论文
共 50 条
  • [41] Exploring cell compatibility of a fibronectin-functionalized physically crosslinked poly(vinyl alcohol) hydrogel
    Millon, Leonardo E.
    Padavan, Donna T.
    Hamilton, Amanda M.
    Boughner, Derek R.
    Wan, Wankei
    JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART B-APPLIED BIOMATERIALS, 2012, 100B (01) : 1 - 10
  • [42] Lamellar phase behavior and molecular interaction of a thermoresponsive poloxamer and crosslinked poly (vinyl alcohol) hydrogel
    Kamlungmak, Sukanjana
    Dechraksa, Janwit
    Padmavathi, Alwar Ramanujam
    Sawatdee, Somchai
    Tinpun, Kittiya
    Nakpheng, Titpawan
    Srichana, Teerapol
    MATERIALS TODAY COMMUNICATIONS, 2019, 20
  • [43] Glutaraldehyde-Crosslinked Poly(vinyl alcohol) Hydrogel Discs for the Controlled Release of Antidiabetic Drug
    More, Swapnil M.
    Kulkarni, Raghavendra V.
    Sa, Biswanath
    Kayane, Navanath V.
    JOURNAL OF APPLIED POLYMER SCIENCE, 2010, 116 (03) : 1732 - 1738
  • [44] Fabrication of poly(vinyl alcohol) hydrogel beads crosslinked using sodium sulfate for microorganism immobilization
    Takei, Takayuki
    Ikeda, Kaoru
    Ijima, Hiroyuki
    Kawakami, Koei
    PROCESS BIOCHEMISTRY, 2011, 46 (02) : 566 - 571
  • [45] Preparation of poly(vinyl amine)-grafted crosslinked poly(vinyl alcohol) microspheres
    Gao, Baojiao
    Lu, Jinhua
    Zhuang, Rubin
    Zhang, Guohai
    Journal of Applied Polymer Science, 2009, 114 (06): : 3487 - 3494
  • [46] Preparation of Poly(vinyl amine)-Grafted Crosslinked Poly(vinyl alcohol) Microspheres
    Gao, Baojiao
    Lu, Jinhua
    Zhuang, Rubin
    Zhang, Guohai
    JOURNAL OF APPLIED POLYMER SCIENCE, 2009, 114 (06) : 3487 - 3494
  • [47] Evaluation of Compliance of Poly (vinyl alcohol) Hydrogel for Development of Arterial Biomodeling
    Kosukegawa, H.
    Mamada, K.
    Kuroki, K.
    Liu, L.
    Inoue, K.
    Hayase, T.
    Ohta, M.
    13TH INTERNATIONAL CONFERENCE ON BIOMEDICAL ENGINEERING, VOLS 1-3, 2009, 23 (1-3): : 1993 - +
  • [48] A photopolymerized composite hydrogel and surgical implanting tool for a nucleus pulposus replacement
    Schmocker, Andreas
    Khoushabi, Azadeh
    Frauchiger, Daniela A.
    Gantenbein, Benjamin
    Schizas, Constantin
    Moser, Christophe
    Bourban, Pierre-Etienne
    Pioletti, Dominique P.
    BIOMATERIALS, 2016, 88 : 110 - 119
  • [49] Curing kinetics and mechanical properties of a composite hydrogel for the replacement of the nucleus pulposus
    Borges, A. C.
    Bourban, P. -E.
    Pioletti, D. P.
    Manson, J. -A. E.
    COMPOSITES SCIENCE AND TECHNOLOGY, 2010, 70 (13) : 1847 - 1853
  • [50] Viscoelastic properties of a novel hydrogel/foam composites for nucleus pulposus replacement
    Raheem, Hassan Mansour
    Bay, Brian
    Rochefort, Skip
    SN APPLIED SCIENCES, 2019, 1 (08):