Development of a Chemically Crosslinked Poly(vinyl alcohol) Hydrogel for Injectable Nucleus Pulposus Replacement

被引:0
|
作者
Binetti, V. R. [1 ]
Marcolongo, M. [1 ]
Lowman, A. M. [2 ]
机构
[1] Drexel Univ, Mat Sci & Engn, Philadelphia, PA 19104 USA
[2] Temple Univ, Dept Bioengn, Philadelphia, PA 19122 USA
基金
美国国家科学基金会;
关键词
D O I
暂无
中图分类号
R318 [生物医学工程];
学科分类号
0831 ;
摘要
Poly(vinyl alcohol) (PVA) hydrogels have been chemically crosslinked using poly(ethylene glycol) diglycidyl ether (PEG-DGE) to develop a material for injectable nucleus pulposus replacement. The effects of PVA and PEG-DGE concentrations on compressive modulus and swelling have been deteremined in addition to the cytotoxic effects of crosslinking PVA with PEG-DGE.
引用
收藏
页码:378 / +
页数:2
相关论文
共 50 条
  • [21] Effects of Microcrystallites on Swelling Behavior in Chemically Crosslinked Poly(vinyl alcohol) Gels
    Otsuka, Emiko
    Kudo, Shuhei
    Sugiyama, Masaaki
    Suzuki, Atsushi
    JOURNAL OF POLYMER SCIENCE PART B-POLYMER PHYSICS, 2011, 49 (02) : 96 - 102
  • [22] Characterization of poly(vinyl alcohol) hydrogel for prosthetic intervertebral disc nucleus
    Darwis, D
    Stasica, P
    Razzak, MT
    Rosiak, JM
    RADIATION PHYSICS AND CHEMISTRY, 2002, 63 (3-6) : 539 - 542
  • [23] Towards a functional radiopaque hydrogel for nucleus pulposus replacement
    Boelen, Erik J. H.
    Koole, Leo H.
    van Rhijn, Lodewijk W.
    van Hooy-Corstjens, Catharina S. J.
    JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART B-APPLIED BIOMATERIALS, 2007, 83B (02) : 440 - 450
  • [24] Nanofibrillated cellulose composite hydrogel for the replacement of the nucleus pulposus
    Borges, Ana C.
    Eyholzer, Christian
    Duc, Fabien
    Bourban, Pierre-Etienne
    Tingaut, Philippe
    Zimmermann, Tanja
    Pioletti, Dominique P.
    Manson, Jan-Anders E.
    ACTA BIOMATERIALIA, 2011, 7 (09) : 3412 - 3421
  • [25] High performance ultrafiltration composite membranes based on poly(vinyl alcohol) hydrogel coating on crosslinked nanofibrous poly(vinyl alcohol) scaffold
    Wang, Xuefen
    Fang, Dufei
    Yoon, Kyunghwan
    Hsiao, Benjamin S.
    Chu, Benjamin
    JOURNAL OF MEMBRANE SCIENCE, 2006, 278 (1-2) : 261 - 268
  • [26] Crosslinked poly(vinyl alcohol) membranes
    Bolto, Brian
    Tran, Thuy
    Hoang, Manh
    Xie, Zongli
    PROGRESS IN POLYMER SCIENCE, 2009, 34 (09) : 969 - 981
  • [27] Irreversible Swelling Behavior and Reversible Hysteresis in Chemically Crosslinked Poly(vinyl alcohol) Gels
    Kamemaru, Keiichiro
    Usui, Shintaro
    Hirashima, Yumiko
    Suzuki, Atsushi
    GELS, 2018, 4 (02)
  • [28] Preparation and characterization of chitosan/poly(vinyl alcohol) chemically crosslinked blends for biomedical applications
    Costa-Junior, Ezequiel S.
    Barbosa-Stancioli, Edel F.
    Mansur, Alexandra A. P.
    Vasconcelos, Wander L.
    Mansur, Herman S.
    CARBOHYDRATE POLYMERS, 2009, 76 (03) : 472 - 481
  • [29] Formation of the first injectable poly(vinyl alcohol) hydrogel by mixing of functional PVA precursors
    Ossipov, Dmitri A.
    Brannvall, Karin
    Forsberg-Nilsson, Karin
    Hilborn, Jons
    JOURNAL OF APPLIED POLYMER SCIENCE, 2007, 106 (01) : 60 - 70
  • [30] Electrically controlled release of sulfosalicylic acid from crosslinked, poly(vinyl alcohol) hydrogel
    Juntanon, Kanokporn
    Niamlang, Sumonman
    Rujiravanit, Ratana
    Sirivat, Anuvat
    INTERNATIONAL JOURNAL OF PHARMACEUTICS, 2008, 356 (1-2) : 1 - 11