Optical coherence tomography in diagnosis and monitoring multiple sclerosis

被引：9

作者：

Kucharczuk, Jan ^{[1
]}

Maciejek, Zdzislaw ^{[2
]}

Sikorski, Bartosz L. ^{[3
]}

机构：

[1] 10th Mil Res Hosp Polyclin, Dept Ophthalmol, Bydgoszcz, Poland

[2] 10th Mil Res Hosp Polyclin, Dept Neurol, Bydgoszcz, Poland

[3] Nicolaus Copernicus Univ, Dept Ophthalmol, M Sklodowskiej Curie 9 St, PL-85094 Bydgoszcz, Poland

来源：

NEUROLOGIA I NEUROCHIRURGIA POLSKA | 2018年 / 52卷 / 02期

关键词：

Multiple sclerosis; Optical coherence tomography; Retinal nerve fiber layer; Ganglion cell layer; NERVE-FIBER LAYER; MICROCYSTIC MACULAR EDEMA; VISUAL DYSFUNCTION; AXONAL LOSS; BRAIN ATROPHY; MATTER DAMAGE; THICKNESS; PATHOLOGY; DISABILITY; RADIATION;

D O I：

10.1016/j.pjnns.2017.10.009

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

This paper presents application of optical coherence tomography (OCT) for diagnosis and monitoring of multiple sclerosis (MS). The peripapillary retinal nerve fibre layer thinning and the reduced total macular volume analysis are shown. With the course of the MS, the severity of these abnormalities increases which reflects the progressive degeneration of retinal ganglion cells and nerve fibres. The OCT parameters are sensitive, non-invasive indicators useful in assessing the progression of inflammation and neurodegeneration in MS. (c) 2017 Polish Neurological Society. Published by Elsevier Sp. z o.o. All rights reserved.

引用

页码：140 / 149

页数：10

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