Catalytic TMSCI promoted powerful aldol addition and Claisen condensation mediated by TiCl4/Bu3N agent:: Comparison and evaluation with the Mukaiyama aldol addition

被引：49

作者：

Yoshida, Y ^{[1
]}

Matsumoto, N ^{[1
]}

Hamasaki, R ^{[1
]}

Tanabe, Y ^{[1
]}

机构：

[1] Kwansei Gakuin Univ, Sch Sci, Nishinomiya, Hyogo 6628501, Japan

来源：

TETRAHEDRON LETTERS | 1999年 / 40卷 / 22期

关键词：

D O I：

10.1016/S0040-4039(99)00682-6

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

TMSCl catalyst (0.05 equiv) signifiantly promoted the TiCl4/Bu3N-mediated direct cross aldol additions of sterically crowded ketones and alpha-hetero substituted ketones, and also the direct Claisen condensation between methyl esters. (C) 1999 Elsevier Science Ltd. All rights reserved.

引用

页码：4227 / 4230

页数：4

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