RETRACTED: Evaluation of residual neuromuscular blockade using modified double burst stimulation (Retracted article. See vol. 63, pg. 561, 2019)

被引:6
|
作者
Saitoh, Y [1 ]
Nakazawa, K [1 ]
Makita, K [1 ]
Tanaka, H [1 ]
Toyooka, H [1 ]
机构
[1] TORIDE KYODO GEN HOSP, DEPT ANESTHESIOL, IBARAKI, OSAKA, JAPAN
关键词
double burst stimulation; train-of-four; vecuronium;
D O I
10.1111/j.1399-6576.1997.tb04776.x
中图分类号
R614 [麻醉学];
学科分类号
100217 ;
摘要
Background: To assess the degree of residual neuromuscular blockade, double burst stimulation (DBS) is commonly applied in the clinical setting. However, fades in response to DBS3,3 can rarely be identified manually when train-of-four (TOF) ratios are greater than or equal to 0.70, and, in contrast, fades in response to DBS3,2 are felt manually in an undesirably high proportion of cases, even at TOF ratios greater than 0.7. We investigated whether a new monitoring method, modified DBS, would be useful to determine an adequate degree of recovery from neuromuscular blockade. For modified DBS, two burst stimuli were applied at an interval of 750 ms. The first stimulation in the modified DBS consisted of two stimuli of 0.3 ms duration at 50 Hz and the second of two stimuli of 0.2 ms duration at 50 Hz. Methods: Forty-five adult patients undergoing elective nitrous oxide-oxygen-isoflurane anesthesia were randomly divided into one of three groups: DBS3,3 group (n=15), DBS3,2 group (n=15), or modified DBS group (n=15). During recovery from vecuronium-induced neuromuscular blockade, on both forearms, DBS3,3, DBS3,2, and modified DBS were delivered in the DBS3,3 group, DBS3,2 group, and modified DBS group, respectively. One hand and forearm (fixed arm) were immobilized to quantify the degree of neuromuscular blockade mechanically, and the contralateral arm (free arm) was unrestrained. An observer determined tactilely on the free arm the presence or absence of fade in response to the three DBS patterns. Results: Probabilities of detection of fade in response to the DBS3,3 were 67% (TOF ratio of 0.51-0.60), 40% (0.61-0.70), 19% (0.71-0.80), 5% (0.81-0.90), and 0% (0.91-1.00). Those to the DBS3,2 were 95% (0.51-0.60), 93% (0.61-0.70), 83% (0.71-0.80), 65% (0.81-0.90), and 38% (0.91-1.00). Those to modified DBS were 90% (0.51-0.60), 86% (0.61-0.70), 65% (0.71-0.80), 25% (0.81-0.90), and 3% (0.91-1.00). The modified DBS was more sensitive in diagnosing residual neuromuscular blockade than DBS3,3 at the TOF ratio of 0.51-0.90, but was less sensitive than DBS3,2 at the TOF ratio of 0.81-1.00 (P<0.05). Conclusion: Our results indicate that the modified DBS may be a useful stimulation pattern to diagnose the adequacy of recovery from neuromuscular blockade.
引用
收藏
页码:741 / 745
页数:5
相关论文
共 50 条
  • [31] RETRACTED: Optimization of Biodiesel Production Using a Magnetically Stabilized Fluidized Bed Reactor (Retracted article. See vol. 55, pg. 561, 2013)
    Guo, Pingmei
    Huang, Fenghong
    Huang, Qingde
    Zheng, Chang
    JOURNAL OF THE AMERICAN OIL CHEMISTS SOCIETY, 2012, 89 (03) : 497 - 504
  • [32] RETRACTED: Imidazolyl-PEI modified nanoparticles for enhanced gene delivery (Retracted article. See vol. 560, pg. 416, 2019)
    Swami, Archana
    Aggarwal, Anita
    Pathak, Atul
    Patnaik, Soma
    Kumar, P.
    Singh, Y.
    Gupta, K. C.
    INTERNATIONAL JOURNAL OF PHARMACEUTICS, 2007, 335 (1-2) : 180 - 192
  • [33] RETRACTED: Monitoring of neuromuscular block after administration of vecuronium in patients with diabetes mellitus (Retracted article. See vol. 122, pg. 156, 2019)
    Saitoh, Y
    Kaneda, K
    Hattori, H
    Nakajima, H
    Murakawa, M
    BRITISH JOURNAL OF ANAESTHESIA, 2003, 90 (04) : 480 - 486
  • [34] RETRACTED: Inaccuracy in traffic forecasts (Retracted article. See vol. 32, pg. 265, 2012)
    Flyvbjerg, B
    Holm, MKS
    Buhl, SL
    TRANSPORT REVIEWS, 2006, 26 (01) : 1 - 24
  • [35] RETRACTED: Cryptomycota: the missing link (Retracted article. See vol. 5, pg. 883, 2014)
    Bolla, Krishna
    Ashforth, Elizabeth Jane
    PROTEIN & CELL, 2012, 3 (03) : 161 - 162
  • [36] RETRACTED: The Influence of Mood on Attribution (Retracted article. See vol. 38, pg. 1378, 2012)
    Avramova, Yana R.
    Stapel, Diederik A.
    Lerouge, Davy
    PERSONALITY AND SOCIAL PSYCHOLOGY BULLETIN, 2010, 36 (10) : 1360 - 1371
  • [37] RETRACTED: Use of albumin: an update (Retracted article. See vol. 125, pg. 417, 2020)
    Boldt, J.
    BRITISH JOURNAL OF ANAESTHESIA, 2010, 104 (03) : 276 - 284
  • [38] RETRACTED: The role of eosinophils in immunotherapy (Retracted article. See vol. 20, pg. 329, 2020)
    Cafone, Joseph
    Ruffner, Melanie A.
    Spergel, Jonathan M.
    CURRENT OPINION IN ALLERGY AND CLINICAL IMMUNOLOGY, 2020, 20 (02) : 194 - 201
  • [39] RETRACTED: Around the void: on the trivial (Retracted article. See vol. 42, pg. 359, 2015)
    Barnett, R. -L. Etienne
    NEOHELICON, 2013, 40 (01) : 99 - 114
  • [40] RETRACTED: Lithium in the treatment of neutropenia (Retracted article. See vol. 19, pg. 241, 2012)
    Petrini, Mario
    Azzara, Antonio
    CURRENT OPINION IN HEMATOLOGY, 2012, 19 (01) : 52 - 57