A NOVEL SCORING SYSTEM FOR TERM-EQUIVALENT-AGE CRANIAL ULTRASOUND IN EXTREMELY PRETERM INFANTS

被引:18
作者
Skiold, Beatrice [1 ,2 ]
Hallberg, Boubou [2 ,3 ]
Vollmer, Brigitte [1 ,4 ]
Aden, Ulrika [1 ,2 ]
Blennow, Mats [2 ,3 ]
Horsch, Sandra [2 ,5 ]
机构
[1] Karolinska Inst, Dept Womens & Childrens Hlth, Stockholm, Sweden
[2] Karolinska Univ Hosp, Dept Neonatol, Stockholm, Sweden
[3] Karolinska Inst, Dept Clin Sci Intervent & Technol CLINTEC, Stockholm, Sweden
[4] Univ Southampton, Fac Med, Clin & Expt Sci, Southampton, England
[5] Helios Klinkum Berlin Buch, Dept Neonatol, Berlin, Germany
基金
英国医学研究理事会;
关键词
Brain injury; Cerebral palsy; Magnetic resonance imaging; Neonate; Neurodevelopmental outcome; White matter abnormalities; Prognosis; Ultrasound; ACTIVE PERINATAL-CARE; NEURODEVELOPMENTAL OUTCOMES; NEONATAL BRAIN; CEREBRAL-PALSY; MRI; ABNORMALITIES; PREDICT;
D O I
10.1016/j.ultrasmedbio.2018.11.005
中图分类号
O42 [声学];
学科分类号
070206 ; 082403 ;
摘要
The role of term-equivalent-age (TEA) cranial ultrasound (cUS) in predicting outcome in preterm infants is increasingly being recognized. However, a detailed quantitative scoring system that allows comparison of groups and comparison with TEA magnetic resonance imaging (MRI) scoring systems is lacking. Eighty-four extremely preterm infants underwent cUS and MRI at TEA. Cranial US was evaluated using a novel detailed scoring system. Agreement between cUS and MRI scores was good (Spearman's p = 0.51, p < 0.001). Outcome at 30 mo corrected was assessed in 66 of 84 preterm and 85 term-born infants. Sensitivity was the same for cUS and MRI in prediction of cerebral palsy (75%) and severe cognitive delay (100%); the specificity was slightly higher for MRI (cerebral palsy: 97% vs. 90%, severe cognitive delay: 95% vs. 90%). The proposed novel cUS scoring system is a helpful tool in quantitative assessment of cUS at TEA and prediction of outcome at 30 mo. (C) 2018 World Federation for Ultrasound in Medicine & Biology. All rights reserved.
引用
收藏
页码:786 / 794
页数:9
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