Transforming Growth Factor-β in Thoracic Aortic Aneurysms: Good, Bad, or Irrelevant?

被引：33
|
作者：
Daugherty, Alan [1 ,2 ]
Chen, Zheying [1 ,2 ]
Sawada, Hisashi [1 ]
Rateri, Debra L. [1 ]
Sheppard, Mary B. [1 ,3 ,4 ]
机构：
[1] Univ Kentucky, Saha Cardiovasc Res Ctr, B243 Biomed Biol Sci Res Bldg, Lexington, KY 40536 USA
[2] Univ Kentucky, Dept Physiol, Lexington, KY USA
[3] Univ Kentucky, Dept Family Med, Lexington, KY USA
[4] Univ Kentucky, Dept Surg, Lexington, KY USA
来源：
JOURNAL OF THE AMERICAN HEART ASSOCIATION | 2017年 / 6卷 / 01期
关键词：
Editorials; aneurysm; cytokine; transforming growth factor-beta pathway aneurysm; vascular biology; SMOOTH-MUSCLE-CELLS; MARFAN-SYNDROME; ANGIOTENSIN-II; MICE; PROGRESSION; DISSECTION; PROTECTS; RECEPTOR;
D O I：
10.1161/JAHA.116.005221
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
引用
收藏
页数：3
相关论文
共 50 条
  • [1] The Pathogenic Transforming Growth Factor-β Overdrive Hypothesis in Aortic Aneurysms and Dissections A Mirage?
    Mallat, Ziad
    Ait-Oufella, Hafid
    Tedgui, Alain
    CIRCULATION RESEARCH, 2017, 120 (11) : 1718 - 1720
  • [2] Transforming Growth Factor-β and the Renin-Angiotensin System in Syndromic Thoracic Aortic Aneurysms: Implications for Treatment
    van Dorst, Daan C. H.
    de Wagenaar, Nathalie P.
    Van der Pluijm, Ingrid
    Roos-Hesselink, Jolien W.
    Essers, Jeroen
    Danser, A. H. Jan
    CARDIOVASCULAR DRUGS AND THERAPY, 2021, 35 (06) : 1233 - 1252
  • [3] Transforming growth factor-β and abdominal aortic aneurysms
    Wang, Yutang
    Krishna, Smriti
    Walker, Philip J.
    Norman, Paul
    Golledge, Jonathan
    CARDIOVASCULAR PATHOLOGY, 2013, 22 (02) : 126 - 132
  • [4] Mutations in transforming growth factor-β receptor type II cause familial thoracic aortic aneurysms and dissections
    Pannu, H
    Fadulu, V
    Chang, J
    Lafont, A
    Hasham, SN
    Sparks, E
    Giampietro, PF
    Zaleski, C
    Estrera, AL
    Safi, HJ
    Shete, S
    Willing, MC
    Raman, CS
    Milewicz, DM
    CIRCULATION, 2005, 112 (04) : 513 - 520
  • [5] Transforming Growth Factor-β Signaling in Thoracic Aortic Aneurysm Development: A Paradox in Pathogenesis
    Jones, Jeffrey A.
    Spinale, Francis G.
    Ikonomidis, John S.
    JOURNAL OF VASCULAR RESEARCH, 2009, 46 (02) : 119 - 137
  • [6] Transforming Growth Factor-β and the Renin-Angiotensin System in Syndromic Thoracic Aortic Aneurysms: Implications for Treatment
    Daan C.H. van Dorst
    Nathalie P. de Wagenaar
    Ingrid van der Pluijm
    Jolien W. Roos-Hesselink
    Jeroen Essers
    A.H. Jan Danser
    Cardiovascular Drugs and Therapy, 2021, 35 : 1233 - 1252
  • [7] Autophagy Signaling and Oxidative Stress in Thoracic Aortic Aneurysms Good, Bad, or Ugly?
    Park, Arick C.
    Yeh, Yu-Sheng
    Rodriguez-Velez, Astrid
    Zhang, Xiangyu
    Razani, Babak
    JACC-BASIC TO TRANSLATIONAL SCIENCE, 2021, 6 (9-10): : 731 - 733
  • [8] TGF-β (Transforming Growth Factor-β) Signaling Protects the Thoracic and Abdominal Aorta From Angiotensin II-Induced Pathology by Distinct Mechanisms
    Angelov, Stoyan N.
    Hu, Jie Hong
    Wei, Hao
    Airhart, Nathan
    Shi, Minghui
    Dichek, David A.
    ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, 2017, 37 (11) : 2102 - +
  • [9] Differential expression of Hedgehog/Notch and transforming growth factor-β in human abdominal aortic aneurysms
    Doyle, Adam J.
    Redmond, Eileen M.
    Gillespie, David L.
    Knight, Peter A.
    Cullen, John P.
    Cahill, Paul A.
    Morrow, David J.
    JOURNAL OF VASCULAR SURGERY, 2015, 62 (02) : 464 - 470
  • [10] When Good Transforming Growth Factor-β Turns Bad in Hepatocellular Carcinoma: Axl Takes the Stage
    Calvisi, Diego F.
    HEPATOLOGY, 2015, 61 (03) : 759 - 761
12345