Recurrent SETBP1 Mutations in Atypical Chronic Myeloid Leukemia Abrogate an Ubiquitination Site and Dysregulate SETBP1 Protein Levels

被引：0
|
作者：
Gambacorti-Passerini, Carlo [1 ]
Valletta, Simona
Winkelmann, Nils [2 ]
Redaelli, Sara
Spinelli, Roberta
Pirola, Alessandra
Antolini, Laura [3 ]
Mologni, Luca
Donadoni, Carla
Papaemmanuil, Elli [4 ]
Schnittger, Susanne [5 ]
Dong-Wook, Kim [6 ]
Boultwood, Jacqueline [7 ]
Rossi, Fabio [8 ]
Gaipa, Giuseppe [9 ]
De Martini, Greta
di Celle, Paola Francia [10 ]
Jang, Hyun G. [11 ]
Fantin, Valeria [11 ]
Bignell, Graham R.
Magistroni, Vera
Haferlach, Torsten [5 ]
Pogliani, Enrico Maria [12 ]
Campbell, Peter [4 ]
Chase, Andrew J. [13 ]
Tapper, William J. [13 ]
Cross, Nicholas C. P. [14 ]
Piazza, Rocco
机构：
[1] San Gerardo Hosp, Hematol & Clin Res Unit, Monza, Italy
[2] Wessex Reg Genet Lab, Salisbury, Wilts, England
[3] Univ Milano Bicocca, Ctr Biostat Clin Epidemiol, Monza, Italy
[4] Wellcome Trust Sanger Inst, Canc Genome Project, Cambridge, England
[5] MLL Munich Leukemia Lab, Munich, Germany
[6] Catholic Univ Korea, Div Hematol, Seoul St Marys Hosp, Seoul, South Korea
[7] Univ Oxford, Radcliffe Dept Med, Oxford, England
[8] San Gerardo Hosp, Immunotransfus Unit, Monza, Italy
[9] Univ Milano Bicocca, Pediat Clin, M Tettamanti Res Ctr, Monza, Italy
[10] Az Osped S Giovanni Battista, CeRMS, Lab Oncol Mol, SCDU Anat Patol 2, Turin, Italy
[11] Agios Phamnceut, Cambridge, MA USA
[12] Osped San Gerardo, HSCT Adult Unit, Monza, Italy
[13] Univ Southampton, Wessex Reg Genet Lab, Salisbury, Wilts, England
[14] Univ Southampton, Wessex Reg Genet Lab, Southampton, Hants, England
来源：
BLOOD | 2012年 / 120卷 / 21期
关键词：
D O I：
暂无
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
2
引用
收藏
页数：2
相关论文
共 50 条
  • [21] Roles of Setbp1 in developmental hematopoiesis and acute myeloid leukemia
    Ao, Fei
    Chen, Fan
    Lv, Minhong
    Cao, Yuming
    Xu, Jinfeng
    Xu, Jingbo
    Leung, Anskar Yu-Hung
    Yuan, Qiwen
    Wang, Li
    He, Bailiang
    GENES & DISEASES, 2024, 11 (06)
  • [22] MUTATIONAL SPECTRUM OF SETBP1 IN MYELOID NEOPLASMS
    Larson, Daniel
    Viswanatha, David
    Chen, Dong
    He, Rong
    INTERNATIONAL JOURNAL OF LABORATORY HEMATOLOGY, 2019, 41 : 96 - 96
  • [23] Immunopathogenesis and SETBP1 mutation analysis in chronic myelomonocytic leukemia
    Liang, Yan
    Shen, Wen-Yi
    Lu, Rui-Nan
    Wang, Rong
    Qiao, Chun
    Zhang, Jian-Fu
    Li, Jian-Yong
    Zhang, Su-Jiang
    Lu, Hua
    INTERNATIONAL JOURNAL OF CLINICAL AND EXPERIMENTAL PATHOLOGY, 2016, 9 (05): : 5378 - 5387
  • [24] CSF3R Mutations Synergize with CEBPA and SETBP1 Mutations in Acute Myeloid Leukemia and Chronic Neutrophilic Leukemia
    Foley, Amy
    Hughes, Seamus B.
    Meshinchi, Soheil
    Maxson, Julia E.
    BLOOD, 2017, 130
  • [25] Subclonal Mutations in SETBP1 Predict Relapse in Juvenile Myelomonocytic Leukemia
    Stieglitz, Elliot
    Troup, Camille B.
    Gelston, Laura C.
    Chow, Eric D.
    Yu, Kristie B.
    Akutagawa, Jon
    Taylor-Weiner, Amaro N.
    Liu, Y. Lucy
    Emanuel, Peter D.
    Braun, Benjamin S.
    Gerbing, Robert B.
    Alonzo, Todd A.
    Loh, Mignon L.
    BLOOD, 2014, 124 (21)
  • [26] CSF3R, SETBP1 and CALR mutations in chronic neutrophilic leukemia
    Yajuan Cui
    Bing Li
    Robert Peter Gale
    Qian Jiang
    Zefeng Xu
    Tiejun Qin
    Peihong Zhang
    Yue Zhang
    Zhijian Xiao
    Journal of Hematology & Oncology, 7
  • [27] CSF3R, SETBP1 and CALR mutations in chronic neutrophilic leukemia
    Cui, Yajuan
    Li, Bing
    Gale, Robert Peter
    Jiang, Qian
    Xu, Zefeng
    Qin, Tiejun
    Zhang, Peihong
    Zhang, Yue
    Xiao, Zhijian
    JOURNAL OF HEMATOLOGY & ONCOLOGY, 2014, 7
  • [28] SETBP1 dysregulation in congenital disorders and myeloid neoplasms
    Coccaro, Nicoletta
    Tota, Giuseppina
    Zagaria, Antonella
    Anelli, Luisa
    Specchia, Giorgina
    Albano, Francesco
    ONCOTARGET, 2017, 8 (31) : 51920 - 51935
  • [29] SETBP1 mutations in 658 patients with myelodysplastic syndromes, chronic myelomonocytic leukemia and secondary acute myeloid leukemias
    F Damm
    R Itzykson
    O Kosmider
    N Droin
    A Renneville
    V Chesnais
    V Gelsi-Boyer
    S de Botton
    N Vey
    C Preudhomme
    A Clavert
    E Delabesse
    S Park
    D Birnbaum
    M Fontenay
    O A Bernard
    E Solary
    Leukemia, 2013, 27 : 1401 - 1403
  • [30] SETBP1 mutations in 106 patients with therapy-related myeloid neoplasms
    Fabiani, Emiliano
    Falconi, Giulia
    Fianchi, Luana
    Criscuolo, Marianna
    Leone, Giuseppe
    Voso, Maria Teresa
    HAEMATOLOGICA, 2014, 99 (09) : E152 - E153
12345