A Canadian genome-wide association study and meta-analysis confirm HLA as a risk factor for peanut allergy independent of asthma

被引：24

作者：

Asai, Yuka ^{[1
,2
]}

Eslami, Aida ^{[3
]}

van Ginkel, C. Dorien ^{[4
]}

Akhabir, Loubna ^{[3
]}

Wan, Ming ^{[3
]}

Yin, David ^{[3
]}

Ellis, George ^{[3
]}

Ben-Shoshan, Moshe ^{[5
]}

Marenholz, Ingo ^{[6
]}

Martino, David ^{[7
]}

Ferreira, Manuel A.

Allen, Katrina ^{[7
]}

Mazer, Bruce

de Groot, Hans ^{[8
]}

de Jong, Nicolette W.

van Wijk, Roy Gerth ^{[9
]}

Dubois, Anthony E. J.

Grosche, Sarah

Ashley, Sarah

Rueschendorf, Franz ^{[11
]}

Kalb, Birgit ^{[12
]}

Beyer, Kirsten ^{[10
]}

Noethen, Markus M. ^{[13
,27
]}

Lee, Young-Ae ^{[14
]}

Chin, Rick

Cheuk, Stephen ^{[25
]}

Hoffman, Joshua

Jorgensen, Eric ^{[15
,26
]}

Witte, John S.

Melles, Ronald B.

Hong, Xiumei ^{[18
]}

Wang, Xiaobin

Hui, Jennie ^{[16
,21
,23
]}

Musk, Arthur W. ^{[20
]}

Hunter, Michael ^{[19
,24
]}

James, Alan L. ^{[22
]}

Koppelman, Gerard H. ^{[17
,21
]}

Sandford, Andrew J. ^{[3
]}

Clarke, Ann E. ^{[28
]}

Daley, Denise ^{[3
]}

机构：

[1] Queens Univ, Dept Med, Div Dermatol, Kingston, ON, Canada

[2] McGill Univ, Dept Med, Div Expt Med, Montreal, PQ, Canada

[3] Univ British Columbia, Ctr Heart Lung Innovat, Vancouver, BC, Canada

[4] Univ Groningen, Univ Med Ctr Groningen, Dept Pediat Pulmonol & Pediat Allergol, Groningen, Netherlands

[5] Univ Groningen, Univ Med Ctr Groningen, GRIAC Res Inst, Groningen, Netherlands

[6] McGill Univ, Montreal Childrens Hosp, Ctr Hlth,Res Inst, Div Allergy & Immunol,Dept Pediat, Montreal, PQ, Canada

[7] Max Delbruck Ctr Mol Med, Clin Pediat Allergy, Expt & Clin Res Ctr, Berlin, Germany

[8] Univ Med Berlin, Berlin, Germany

[9] Univ Melbourne, Royal Childrens Hosp, Murdoch Childrens Res Inst, Melbourne, Vic, Australia

[10] QIMR Berghofer Med Res Inst, Brisbane, Qld, Australia

[11] Diaconessenhuis Voorburg Reinier Graaf Gasthuis, Dept Pediat Allergol, Delft, Netherlands

[12] Erasmus MC, Dept Allergol, Rotterdam, Netherlands

[13] Univ Melbourne, Dept Paediat, Royal Childrens Hosp, Murdoch Childrens Res Inst, Melbourne, Vic, Australia

[14] Hudson Inst Med Res, Clayton, Vic, Australia

[15] Max Delbruck Ctr Mol Med, Berlin, Germany

[16] Charite Univ Med Berlin, Dept Pediat Pneumol & Immunol, Berlin, Germany

[17] Univ Bonn, Sch Med, Inst Human Genet, Bonn, Germany

[18] Univ Hosp Bonn, Bonn, Germany

[19] Univ Calgary, Cumming Sch Med, Dept Med, Div Rheumatol, Calgary, AB, Canada

[20] Univ Calif San Francisco, Dept Epidemiol & Biostat, San Francisco, CA 94143 USA

[21] Kaiser Permanente Northern Calif, Div Res, Oakland, CA USA

[22] Kaiser Permanente Northern Calif, Redwood City Med Ctr, Dept Ophthalmol, Redwood City, CA USA

[23] Johns Hopkins Univ Bloomberg, Sch Publ Hlth, Ctr Early Life Origins Dis, Family & Reprod Hlth,Dept Populat, Baltimore, MD USA

[24] Univ Western Australia, Australia & Pathol & Lab Med, Sch Populat Hlth, Crawley, WA, Australia

[25] Univ Western Australia, Sir Charles Gairdner Hosp, Dept Resp Med, Perth, WA, Australia

[26] Univ Western Australia, Sch Populat Hlth, Perth, WA, Australia

[27] Univ Western Australia, Dept Pulm Physiol & Sleep Med, Sir Charles Gairdner Hosp, Perth, WA, Australia

[28] Univ Western Australia, Sch Med & Pharmacol, Perth, WA, Australia

来源：

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY | 2018年 / 141卷 / 04期

基金：

加拿大健康研究院; 英国医学研究理事会; 美国国家卫生研究院; 加拿大自然科学与工程研究理事会; 澳大利亚研究理事会;

关键词：

EXPRESSION; GENE;

D O I：

10.1016/j.jaci.2017.10.047

中图分类号：

R392 [医学免疫学];

学科分类号：

100102 ;

摘要：

[No abstract available]

引用

页码：1513 / +

页数：4

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