Coproduction of EPA and Fucoxanthin withP. tricornutum- A Promising Approach for Up- and Downstream Processing

被引：52
作者：
Derwenskus, Felix [1 ,2 ]
Schaefer, Benjamin [2 ]
Mueller, Jan [2 ]
Frick, Konstantin [2 ]
Gille, Andrea [3 ]
Briviba, Karlis [3 ]
Schmid-Staiger, Ulrike [1 ]
Hirth, Thomas [4 ]
机构：
[1] Fraunhofer Inst Interfacial Engn & Biotechnol IGB, Nobelstr 12, D-70569 Stuttgart, Germany
[2] Univ Stuttgart, Inst Interfacial Proc Engn & Plasma Technol IGVP, Nobelstr 12, D-70569 Stuttgart, Germany
[3] Max Rubner Inst, Fed Res Inst Nutr & Food, Haid & Neu Str 9, D-76131 Karlsruhe, Germany
[4] Karlsruhe Inst Technol, Kaiserstr 12, D-76131 Karlsruhe, Germany
来源：
CHEMIE INGENIEUR TECHNIK | 2020年 / 92卷 / 11期
关键词：
Eicosapentaenoic acid; Carotenoids; Diatom; Light availability; Pressurized liquid extraction; ACCELERATED SOLVENT-EXTRACTION; POLYUNSATURATED FATTY-ACIDS; IMPROVED LIGHT UTILIZATION; PHAEODACTYLUM-TRICORNUTUM; EICOSAPENTAENOIC ACID; CHROMATIC ADAPTATION; ANTIOXIDANT ACTIVITY; CHLORELLA-VULGARIS; CULTURE-CONDITIONS; FLUID EXTRACTION;
D O I：
10.1002/cite.202000046
中图分类号：
TQ [化学工业];
学科分类号：
0817 ;
摘要：
Eicosapentaenoic acid (EPA) and fucoxanthin, a carotenoid, provide a broad variety of health benefits in human nutrition. In this study, an up- and downstream process for the coproduction of EPA and fucoxanthin using the diatomPhaeodactylum tricornutumin flat-panel airlift photobioreactors is proposed. The approach represents a promising alternative to conventional sources for both compounds, viz. marine fish and macroalgae. The productivity as well as the biomass-specific product content were optimized during cultivation. Subsequently, both compounds were extracted, separated and purified using pressurized liquids.
引用
收藏
页码：1780 / 1789
页数：10
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