Are surrogate markers adequate to assess cardiovascular disease drugs?

被引：221

作者：

Temple, R ^{[1
]}

机构：

[1] US FDA, Ctr Drug Evaluat & Res Policy, Rockville, MD 20857 USA

来源：

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION | 1999年 / 282卷 / 08期

关键词：

D O I：

10.1001/jama.282.8.790

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

引用

页码：790 / 795

页数：8

共 30 条

[1]

Alderman M, 1997, J HYPERTENS, V15, P105

[2]

[Anonymous], 1992, Fed Regist, V57, P58942

[3]

[Anonymous], 1970, JAMA-J AM MED ASSOC, V213, P1143, DOI DOI 10.1001/JAMA.213.7.1143

[4] What have we learned from the calcium channel blocker controversy? [J].

Califf, RM ;

Kramer, JM .

CIRCULATION, 1998, 97 (16) :1529-1531

[5] A dose-dependent increase in mortality with vesnarinone among patients with severe heart failure [J].

Cohn, JN ;

Goldstein, SO ;

Greenberg, BH ;

Lorell, BH ;

Bourge, RC ;

Jaski, BE ;

Gottlieb, SO ;

McGrew, F ;

DeMets, DL ;

White, BG .

NEW ENGLAND JOURNAL OF MEDICINE, 1998, 339 (25) :1810-1816

[6] BLOOD-PRESSURE, STROKE, AND CORONARY HEART-DISEASE .2. SHORT-TERM REDUCTIONS IN BLOOD-PRESSURE - OVERVIEW OF RANDOMIZED DRUG TRIALS IN THEIR EPIDEMIOLOGIC CONTEXT [J].

COLLINS, R ;

PETO, R ;

MACMAHON, S ;

HEBERT, P ;

FIEBACH, NH ;

EBERLEIN, KA ;

GODWIN, J ;

QIZILBASH, N ;

TAYLOR, JO ;

HENNEKENS, CH .

LANCET, 1990, 335 (8693) :827-838

[7] Rationale and design for the antihypertensive and lipid lowering treatment to prevent heart attack trial (ALLHAT) [J].

Davis, BR ;

Cutler, JA ;

Gordon, DJ ;

Furberg, CD ;

Wright, JT ;

Cushman, WC ;

Grimm, RH ;

LaRosa, J ;

Whelton, PK ;

Perry, HM ;

Alderman, MH ;

Ford, CE ;

Oparil, S ;

Francis, C ;

Proschan, M ;

Pressel, S ;

Black, HR ;

Hawkins, CM .

AMERICAN JOURNAL OF HYPERTENSION, 1996, 9 (04) :342-360

[8] MORTALITY AND MORBIDITY IN PATIENTS RECEIVING ENCAINIDE, FLECAINIDE, OR PLACEBO - THE CARDIAC-ARRHYTHMIA SUPPRESSION TRIAL [J].

ECHT, DS ;

LIEBSON, PR ;

MITCHELL, LB ;

PETERS, RW ;

OBIASMANNO, D ;

BARKER, AH ;

ARENSBERG, D ;

BAKER, A ;

FRIEDMAN, L ;

GREENE, HL ;

HUTHER, ML ;

RICHARDSON, DW .

NEW ENGLAND JOURNAL OF MEDICINE, 1991, 324 (12) :781-788

[9] Surrogate end points in clinical trials: Are we being misled? [J].

Fleming, TR ;

DeMets, DL .

ANNALS OF INTERNAL MEDICINE, 1996, 125 (07) :605-613

[10] A cardiologist's perspective on evolving concepts in the management of congestive heart failure [J].

Forker, AD .

JOURNAL OF CLINICAL PHARMACOLOGY, 1996, 36 (11) :973-984

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