High throughput one pot synthesis of 2-methylquinolines

被引：23

作者：

Chandrashekarappa, Kiran Kumar H. ^{[1
]}

Mahadevan, Kittappa M. ^{[1
]}

Manjappa, Kiran B. ^{[2
]}

机构：

[1] Kuvempu Univ, Dept Post Grad Studies & Res Chem, Sch Chem Sci, Shankaraghatta 577451, Karnataka, India

[2] Natl Taiwan Univ Sci & Technol, Taipei 10607, Taiwan

来源：

TETRAHEDRON LETTERS | 2013年 / 54卷 / 11期

关键词：

2-Methylquinolines; Acetic acid; Ethy vinyl ether; aza-Diels-Alder reaction; Aniline; DIELS-ALDER REACTIONS; EFFICIENT SYNTHESIS; ACID; QUINOLINES;

D O I：

10.1016/j.tetlet.2012.12.094

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Various 2-methylquinolines have been successfully synthesized by using anilines and ethyl vinyl ether in 1:3 mole ratios in the presence of acetic acid. Stirring at rt for 3-4 h followed by reflux for 3.5-4 h resulted in the corresponding 2-methylquinolines in good yield. (C) 2012 Elsevier Ltd. All rights reserved.

引用

页码：1368 / 1370

页数：3

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