Efficiency of Selected Mutagens in Generating Xanthophyllomyces dendrorhous Strains Hyperproducing Astaxanthin

被引：11

作者：

Stachowiak, Barbara ^{[1
]}

机构：

[1] Poznan Univ Life Sci, Inst Technol Plant Origin Food, PL-60624 Poznan, Poland

来源：

POLISH JOURNAL OF MICROBIOLOGY | 2013年 / 62卷 / 01期

关键词：

Xanthophyllomyces dendrorhous; astaxanthin; carotenoids; mutagenesis; PHAFFIA-RHODOZYMA; CULTURE; MUTANTS; STATE;

D O I：

10.33073/pjm-2013-008

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Astaxanthin is a xanthophill pigment with commercial application in the aquaculture, pharmaceutical, food and cosmetic industries. The red yeast Xanthophyllomyces dendrorhous is one of the most promising microorganisms for its industrial production. However, astaxanthin content in wild yeast strains is low. Pigment production by X. dendrorhous can be improved by mutagenesis. The aim of the study was to assess the efficiency of four mutagens: UV radiation, benomyl, ethyl methanesulfonate and ethidium bromide in generating asthaxanthin-hyperproducing strains of the yeast Xanthophyllomyces dendrorhous DSM 5626. Mutations with benomyl, ethidium bromide and UV radiation generated a group of hyperpigmented mutants exhibiting increases up to 100% in astaxanthin content. Ethyl methanesulfonate turned out to be useless in this respect.

引用

页码：67 / 72

页数：6

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