Zebrafish and Xenopus tadpoles:: Small animal models to study angiogenesis and lymphangiogenesis

被引：51
|
作者：
Ny, A [1 ]
Autiero, M [1 ]
Carmeliet, P [1 ]
机构：
[1] Katholieke Univ Leuven, Flinders Interuniv Inst Biotechnol, Ctr Transgene Technol & Gene Therapy, B-3000 Louvain, Belgium
来源：
EXPERIMENTAL CELL RESEARCH | 2006年 / 312卷 / 05期
关键词：
angiogenesis; lymphangiogenesis; zebrafish; Xenopus;
D O I：
10.1016/j.yexcr.2005.10.018
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
Small vertebrate organisms have emerged as key players in the post-genomic era for the functional characterization of novel genes on a high-throughput scale. In this context, the zebrafish embryos and Xenopus tadpoles represent attractive and valuable models to rapidly identify and characterize novel genes involved in angiogenesis and lymph angiogenesis-a significant task with a consequent impact on the design of more effective therapeutic strategies. The advantages of these two models will be discussed in the present review. (c) 2005 Elsevier Inc. All rights reserved.
引用
收藏
页码：684 / 693
页数：10
相关论文
共 50 条
  • [21] Angiogenesis in two animal models of osteoarthritis
    Mapp, P. I.
    Avery, P. S.
    McWilliams, D. F.
    Bowyer, J.
    Day, C.
    Moores, S.
    Webster, R.
    Walsh, D. A.
    OSTEOARTHRITIS AND CARTILAGE, 2008, 16 (01) : 61 - 69
  • [22] Tamoxifen, angiogenesis, oestrogens and animal models
    Speirs V.
    Breast Cancer Research, 3 (1)
  • [23] Review of the Ocular Angiogenesis Animal Models
    Montezuma, Sandra R.
    Vavvas, Demetrios
    Miller, Joan W.
    SEMINARS IN OPHTHALMOLOGY, 2009, 24 (02) : 52 - 61
  • [24] IQGAP2 is a novel mediator of Vegf-signaling during zebrafish lymphangiogenesis and angiogenesis
    Bower, Neil
    Kartopawiro, Joelle
    Le Guen, Ludovic
    Karnezis, Tara
    Achen, Marc
    Stacker, Steven
    Francois, Matt
    Hogan, Benjamin
    ANGIOGENESIS, 2014, 17 (04) : 977 - 978
  • [25] Angiogenesis and the Models to Study Angiogenesis
    Mostafaie, Ali
    Motlagh, Hamid Reza Mohammadi
    Mansouri, Kamran
    YAKHTEH, 2010, 11 (04): : 374 - 381
  • [26] Tumors in tadpoles -: the Xenopus embryo as a model system for the study of tumorigenesis
    Wallingford, JB
    TRENDS IN GENETICS, 1999, 15 (10) : 385 - 388
  • [27] Abnormal angiogenesis in zebrafish models for FKRP and fukutin deficiency
    Wood, A. J.
    Jepson, C. D.
    Laval, S. H.
    Bushby, K. M.
    Lochmuller, H.
    Barresi, R.
    Muller, J. S.
    Straub, V.
    NEUROMUSCULAR DISORDERS, 2010, 20 (9-10) : 599 - 600
  • [28] Small Animal Models
    Morais, Alain da Silva
    Oliveira, J. Miguel
    Reis, Rui L.
    OSTEOCHONDRAL TISSUE ENGINEERING: CHALLENGES, CURRENT STRATEGIES, AND TECHNOLOGICAL ADVANCES, 2018, 1059 : 423 - 439
  • [29] Closantel Suppresses Angiogenesis and Cancer Growth in Zebrafish Models
    Zhu, Xiao-Yu
    Xia, Bo
    Liu, Hong-Cui
    Xu, Yi-Qiao
    Huang, Chang-Jiang
    Gao, Ji-Min
    Dong, Qiao-Xiang
    Li, Chun-Qi
    ASSAY AND DRUG DEVELOPMENT TECHNOLOGIES, 2016, 14 (05) : 282 - 290
  • [30] Chick Chorioallantoic Membrane as an in vivo Model for the Study of Angiogenesis and Lymphangiogenesis
    Wan, Zhenzhen
    Hirche, Christoph
    Fricke, Fabia
    Dragu, Adrian
    Will, Patrick A.
    JOURNAL OF VASCULAR RESEARCH, 2024,
12345