Terephthalaldehyde: An Effecient Key Precursor for Novel Synthesis of Some Interesting Bis-thiazoles and Bis-triazolopyrimidinones

被引:11
作者
Gomha, Sobhi M. [1 ]
Farghaly, Thoraya A. [1 ,2 ]
Abbas, Eman M. H. [3 ]
Alqurashi, Nadia T. [2 ]
机构
[1] Cairo Univ, Dept Chem, Fac Sci, Giza 12613, Egypt
[2] Umm Al Qura Univ, Fac Sci Appl, Dept Chem, Makkah El Mukarramah, Saudi Arabia
[3] Natl Res Ctr, Dept Chem Natl & Microbial Prod, Cairo, Egypt
关键词
BIOLOGICAL-ACTIVITY; HYDRAZONOYL HALIDES; FUSED HETEROCYCLES; MOLECULAR DOCKING; DERIVATIVES; INHIBITORS; AGENTS;
D O I
10.1002/jhet.3100
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
Novel bis-thiazoles were synthesized in high and efficient yields from the reaction of thiosemicarbazones with halogenated compounds. Also, new bis-triazolopyrimidines were prepared from the reaction of hydrazonoyl chlorides with bis-thione derivative. All prepared compounds were fully characterized by spectral methods. The synthesized bis-compounds will be attractive species for the medicinal researchers to investigate their biological activity.
引用
收藏
页码:750 / 755
页数:6
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