Three new phloroglucinol derivatives from Hypericum scabrum

被引：14

作者：

Ma, Jie ^{[1
,2
]}

Ji, Teng-Fei ^{[1
,2
]}

Yang, Jian-Bo ^{[1
,2
]}

Wang, Ai-Guo ^{[1
,2
]}

Su, Ya-Lun ^{[1
,2
]}

机构：

[1] Chinese Acad Med Sci, State Key Lab Bioact Subst & Funct Nat Med, Inst Mat Med, Beijing 100050, Peoples R China

[2] Peking Union Med Coll, Beijing 100050, Peoples R China

来源：

JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH | 2012年 / 14卷 / 05期

关键词：

Guttiferae; Hypericum scabrum; phloroglucinol;

D O I：

10.1080/10286020.2012.680445

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

A chemical investigation on the aerial parts of Hypericum scabrum L. resulted in the isolation of three new phloroglucinol derivatives, hyperscabrins A (1), B (2), and C (3), together with one known compound, (2R,3R,4S,6R)-3-methyl-4,6-di(3-methyl-2-butenyl)-2-(2-methyl-1-oxopropyl)-3-(4-methyl-3-pentenyl)-cyclohexanone (4). The structures were elucidated by means of spectroscopic methods, including MS, IR, 1D NMR, and 2D NMR, and the absolute configurations of chiral centers in these phloroglucinol derivatives were determined for the first time by studying their circular dichroism spectra.

引用

页码：508 / 514

页数：7

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