Antibacterial activity and cytotoxicity of essential oil of Lantana Camara L. leaves from Nigeria

被引：0
|
作者：
Sonibare, O. Oluwadayo [1 ]
Effiong, I. [1 ]
机构：
[1] Univ Ibadan, Dept Chem, Ibadan, Nigeria
来源：
AFRICAN JOURNAL OF BIOTECHNOLOGY | 2008年 / 7卷 / 15期
关键词：
Lantana camara L; antimicrobial; cytotoxicity; essential oil; 1,8-cineol; sabinene;
D O I：
暂无
中图分类号：
Q81 [生物工程学（生物技术）]; Q93 [微生物学];
学科分类号：
071005 ; 0836 ; 090102 ; 100705 ;
摘要：
The chemical composition of essential oil obtained from air-dried leaves of Lantana camara L. by hydrodistillation was analyzed by GC and GC-MS. A total of thirty-two compounds representing 74.8% of the oil were identified. The main constituents were 1,8-cineol (15.8%), sabinene (14.7%) and beta-caryophylene (8.9%). The essential oil was tested for antibacterial activity against 6 strains, using disc diffusion method, and for cytotoxicity using brine-shrimp lethality assay. The oil showed moderate activity against Candida albican, Bacillus subtilis, Staphylococcus typhi, Pseudomonas aeruginosa and Bacillus aureus. These activities support its potential use as a remedy for bacterial infectious diseases. The essential oil with LC50 value of 0.01 was found to be highly toxic.
引用
收藏
页码：2618 / 2620
页数：3
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