A glucose-responsive controlled release system using glucose oxidase-gated mesoporous silica nanocontainers

被引：73
|
作者：
Chen, Mengjie [1 ]
Huang, Chusen [1 ]
He, Chunsheng [1 ]
Zhu, Weiping [1 ]
Xu, Yufang [1 ]
Lu, Yunfeng [2 ]
机构：
[1] E China Univ Sci & Technol, Shanghai Key Lab Chem Biol, Sch Pharm, Shanghai 200237, Peoples R China
[2] Univ Calif Los Angeles, Dept Chem & Biomol Engn, Los Angeles, CA 90095 USA
来源：
CHEMICAL COMMUNICATIONS | 2012年 / 48卷 / 76期
基金：
国家高技术研究发展计划(863计划); 中国国家自然科学基金;
关键词：
CONTROLLED DRUG-RELEASE; GUEST MOLECULES; CANCER-CELLS; NANOPARTICLES; DELIVERY; PH; SUPPORTS; CHEMOTHERAPY; NANOSPHERE; INSULIN;
D O I：
10.1039/c2cc34290a
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
A glucose-responsive controlled-release system based on the competitive combination between glucose oxidase, glucosamine and glucose has been described, which exhibits perfect controlled release properties and high selectivity for glucose over other monosaccharides. This paved the way for a new generation of stimuli-responsive delivery systems.
引用
收藏
页码：9522 / 9524
页数：3
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