Perspective in infertility: the ovarian stem cells

被引：31

作者：

Silvestris, Erica ^{[1
]}

D'Oronzo, Stella ^{[2
]}

Cafforio, Paola ^{[2
]}

D'Amato, Giuseppe ^{[3
]}

Loverro, Giuseppe ^{[1
]}

机构：

[1] Univ Bari Aldo Moro, Div Gynecol & Obstet, Dept Biomed Sci & Human Oncol, I-70124 Bari, Italy

[2] Univ Bari Aldo Moro, Div Mol Oncol, Dept Biomed Sci & Human Oncol, I-70124 Bari, Italy

[3] Univ Bari Aldo Moro, Dept Biomed Sci & Human Oncol, ASL Bari, PT Jaia,Reprod & IVF Unit, I-70124 Bari, Italy

来源：

JOURNAL OF OVARIAN RESEARCH | 2015年 / 8卷

关键词：

ADULT MAMMALIAN OVARIES; ACTIVE GERM-CELLS; SURFACE EPITHELIUM; BONE-MARROW; MOUSE; PURIFICATION; FERTILITY; OOCYTES; WOMEN; GENERATION;

D O I：

10.1186/s13048-015-0184-9

中图分类号：

Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Infertility is a medical and social condition that affects millions of women worldwide and is today considered so far as a new disease. A considerable progress has been recently pursued in the field of the reproductive medicine and the infertility treatment may account for novel and modern procedures such as in vitro oocyte fertilization, egg donation, pregnancy surrogacy and preimplantation diagnosis. However, great interest has lately been reserved to the ovarian stem cells (OSCs) whose existence in woman ovaries has been proven. OSCs are thus suitable for developmental studies in infertility and in other clinical applications as endocrine derangements due to premature ovarian failure, or for infertility treatment after cancer chemotherapies, as well as in restoring the hormonal balance in postmenopausal age.

引用

页数：9

共 26 条

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