A theoretical study of the contrast recovery and variance of MAP reconstructions from PET data

被引:141
作者
Qi, JY [1 ]
Leahy, RM [1 ]
机构
[1] Univ So Calif, Inst Signal & Image Proc, Los Angeles, CA 90089 USA
关键词
hyperparameter estimation; image resolution; MAP estimation; variance analysis;
D O I
10.1109/42.768839
中图分类号
TP39 [计算机的应用];
学科分类号
081203 ; 0835 ;
摘要
We examine the spatial resolution and variance properties of PET images reconstructed using maximum a posteriori (MAP) or penalized-likelihood methods. Resolution is characterized by the contrast recovery coefficient (CRC) of the local impulse response. Simplified approximate expressions are derived for the local impulse response CRC's and variances for each voxel, Using these results we propose a practical scheme for selecting spatially variant smoothing parameters to optimize lesion detectability through maximization of the local CRC-to-noise ratio in the reconstructed image.
引用
收藏
页码:293 / 305
页数:13
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