Alternative Strategies for the Derivation of Human Embryonic Stem Cell Lines and the Role of Dead Embryos

被引：3
作者：
Gavrilov, Svetlana [2 ]
Papaioannou, Virginia E. [2 ]
Landry, Donald W. [1 ]
机构：
[1] Columbia Univ, Coll Phys & Surg, Div Expt Therapeut, Dept Med, New York, NY 10032 USA
[2] Columbia Univ, Coll Phys & Surg, Dept Genet & Dev, New York, NY 10032 USA
来源：
CURRENT STEM CELL RESEARCH & THERAPY | 2009年 / 4卷 / 01期
关键词：
Arrested human embryos; ES cell derivation; alternative approaches; human embryonic stem cells; hESC; PREIMPLANTATION GENETIC DIAGNOSIS; AMNIOTIC-FLUID; CLEAVAGE-STAGE; MATERNAL AGE; MORPHOLOGY; INVITRO; FERTILIZATION; ABNORMALITIES; MYOCARDIUM; CULTURE;
D O I：
10.2174/157488809787169057
中图分类号：
Q813 [细胞工程];
学科分类号：
摘要：
The therapeutic potential for human embryonic stem cells (hESC) drives intense public and scientific interest. However, the classical approach for derivation of hESC entails the destruction of human embryos. Controversial ethical issues and correspondingly restrictive federal policies in many countries have prompted the development of alternative approaches for the isolation of hESC. Here, several different strategies are discussed with a focus on the harvesting of live hESC from dead embryos.
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页码：81 / 86
页数：6
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