Synthesis of carbazolones and 3-acetylindoles via oxidative C-N bond formation through PIFA-mediated annulation of 2-aryl enaminones

被引：66
|
作者：
Ban, Xu [1 ]
Pan, Yan [1 ]
Lin, Yingfu [1 ]
Wang, Songqing [1 ]
Du, Yunfei [1 ]
Zhao, Kang [1 ]
机构：
[1] Tianjin Univ, Sch Pharmaceut Sci & Technol, Tianjin Key Lab Modern Drug Deliver & High Effici, Tianjin 300072, Peoples R China
来源：
ORGANIC & BIOMOLECULAR CHEMISTRY | 2012年 / 10卷 / 18期
基金：
中国国家自然科学基金;
关键词：
INDOLE-DERIVATIVES; ARYL ENAMINES; (DIACETOXYIODO)ARENES; CYCLIZATION; IODOARENES; CONVERSION; ROUTE;
D O I：
10.1039/c2ob25348h
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A series of carbazolone derivatives and 3-acetylindoles have been achieved via PIFA-mediated intramolecular cyclization of 2-aryl enaminones. This process allows the N-moiety on the side-chain to be annulated to the benzene ring via the metal-free oxidative aromatic C-N bond formation.
引用
收藏
页码：3606 / 3609
页数：4
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