Synthesis of carbazolones and 3-acetylindoles via oxidative C-N bond formation through PIFA-mediated annulation of 2-aryl enaminones

被引：65

作者：

Ban, Xu ^{[1
]}

Pan, Yan ^{[1
]}

Lin, Yingfu ^{[1
]}

Wang, Songqing ^{[1
]}

Du, Yunfei ^{[1
]}

Zhao, Kang ^{[1
]}

机构：

[1] Tianjin Univ, Sch Pharmaceut Sci & Technol, Tianjin Key Lab Modern Drug Deliver & High Effici, Tianjin 300072, Peoples R China

来源：

ORGANIC & BIOMOLECULAR CHEMISTRY | 2012年 / 10卷 / 18期

基金：

中国国家自然科学基金;

关键词：

INDOLE-DERIVATIVES; ARYL ENAMINES; (DIACETOXYIODO)ARENES; CYCLIZATION; IODOARENES; CONVERSION; ROUTE;

D O I：

10.1039/c2ob25348h

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A series of carbazolone derivatives and 3-acetylindoles have been achieved via PIFA-mediated intramolecular cyclization of 2-aryl enaminones. This process allows the N-moiety on the side-chain to be annulated to the benzene ring via the metal-free oxidative aromatic C-N bond formation.

引用

收藏

页码：3606 / 3609

页数：4

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