The many uses of autophagosomes

被引:7
作者
Amer, Amal O. [1 ]
机构
[1] Ohio State Univ, Dept Microbial Infect & Immun, Columbus, OH 43210 USA
关键词
INDUCTION;
D O I
10.4161/auto.24146
中图分类号
Q2 [细胞生物学];
学科分类号
071009 ; 090102 ;
摘要
Autophagy has emerged as a significant innate immune response to pathogens. Typically, autophagosomes deliver their contents to lysosomes for degradation. Some pathogens such as Salmonella enterica serovar Typhimurium succumb to autophagy and are transported to lysosomes for degradation. Yet, many professional pathogens, including Legionella pneumophila and Burkholderia cenocepacia, subvert this pathway exploiting autophagy to their advantage.
引用
收藏
页码:633 / 634
页数:2
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