A New Method for Determining the Absorbed Dose in a Radiation Field by Using a Thiamine Hydrochloride Aqueous Solution

被引：2

作者：

Li, Ying ^{[1
]}

Lv, Changyin ^{[1
]}

Zhao, Ying ^{[1
]}

Sun, Qiang ^{[1
]}

Li, Yunjing ^{[1
]}

机构：

[1] Univ South China, Inst Environm & Radiat Med, Sch Publ Hlth, Hengyang 421001, Hunan, Peoples R China

来源：

ANALYTICAL SCIENCES | 2013年 / 29卷 / 12期

关键词：

Thiamine hydrochloride; radiation dosimeter; high-performance liquid chromatography (HPLC); mass spectrum; H-1-NMR spectrum; DOSIMETER;

D O I：

10.2116/analsci.29.1189

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

This research investigated the ionizing radiation effect on thiamine hydrochloride (TH) and its usability as an irradiation dosimeter. The fundamental principle is to determine the concentration variations of TH solutions with high-performance liquid chromatography (HPLC) after exposing to gamma-rays. The decreasing peak area of TH in the HPLC chromatogram forms a linear relationship with the rising radiation dose. We investigated the characteristics and suitable application range of the TH as a new radiation dosimeter. The influence factors and mechanism of the reaction induced by radiation were also discussed. According to the correlation between the concentration and the radiation dose, 0.3 g/L of a TH solution is suitable for the 0.1 - 10 kGy dose range, and 2 g/L is appropriate for 0.1 - 20 kGy. The easy availability and the simple, but stable, chemical structure of thiamine makes it a potential candidate for radiation dose research. Also, the preparation proceeding for sampling is easy, and the result can be automatic monitored by liquid chromatography.

引用

页码：1189 / 1194

页数：6