Fertility preservation in women with cervical cancer

被引：21

作者：

Somigliana, Edgardo ^{[1
,2
]}

Mangili, Giorgia ^{[3
]}

Martinelli, Fabio ^{[4
]}

Noli, Stefania ^{[1
,5
]}

Filippi, Francesca ^{[2
]}

Bergamini, Alice ^{[3
]}

Bocciolone, Luca ^{[3
]}

Buonomo, Barbara ^{[5
]}

Peccatori, Fedro ^{[5
]}

机构：

[1] Univ Milan, Dept Clin Sci & Community Hlth, Milan, Italy

[2] Fdn IRCCS Ca Granda Osped Maggiore Policlin, Obstet Gynecol Dept, Milan, Italy

[3] IRCCS Milan, Obstet Gynecol Dept, San Raffaele Sci Inst, Milan, Italy

[4] Fdn IRCCS Natl Canc Inst, Gynecol Oncol Unit, Milan, Italy

[5] European Inst Oncol IRCCS, Div Gynaecol Oncol, Fertil & Procreat Unit, Milan, Italy

来源：

CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY | 2020年 / 154卷

关键词：

Cervical cancer; Fertility preservation; Oocyte; Surrogacy; Uterus transplantation; FERTILIZATION SURROGATE PREGNANCY; UNDERWENT RADICAL HYSTERECTOMY; BONE-MARROW-TRANSPLANTATION; OVARIAN TRANSPOSITION; SPARING SURGERY; UTERUS TRANSPLANTATION; VAGINAL TRACHELECTOMY; UTERINE VOLUME; OUTCOMES; CHEMOTHERAPY;

D O I：

10.1016/j.critrevonc.2020.103092

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Fertility preservation in women with cervical cancer is a demanding but evolving issue. Some remarkable achievements have been reached, in particular the improvement of primary and secondary prevention and the broadening of the indications for conservative surgery up to FIGO 2018 stage IB2. Natural pregnancy rate and the rate of obstetrics complications following conservative approach is satisfactory even if not optimal. On the other hand, the use of classic strategies for fertility preservation such as oocytes or ovarian cortex freezing is extremely limited, being the uterus compromised by treatment in a high proportion of cases. In fact, the availability of uterine surrogacy can play a role in the counseling and the decision-making process. The recent advent of uterus transplantation is fascinating but, at present, cannot be viewed as a realistic solution.

引用

页数：7

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