CITRIN MRNA THERAPY IMPROVED METABOLIC AND BEHAVIORAL ABNORMALITIES IN A MOUSE MODEL OF TYPE II CITRULLINEMIA

被引：0
|
作者：
Cao, Jingsong [1 ]
Finn, Patrick [1 ]
An, Jeff [1 ]
Guey, Lin [1 ]
Galduroz, Mikel [1 ]
Lukacs, Christine [1 ]
Frassetto, Andrea [1 ]
Sabnis, Staci [2 ,3 ]
Murphy-Benenato, Kerry E. [2 ,3 ]
Kumarasinghe, E. Sathyajith [2 ,3 ]
Salerno, Timothy [2 ,3 ]
Saheki, Takeyori [2 ,3 ]
Martini, Paolo [1 ]
机构：
[1] Moderna Therapeut, Rare Dis, Cambridge, MA USA
[2] Moderna Therapeut, Formulat, Cambridge, MA USA
[3] Kagoshima Univ, Dept Mol Oncol, Kagoshima, Japan
来源：
MOLECULAR GENETICS AND METABOLISM | 2018年 / 123卷 / 03期
关键词：
D O I：
暂无
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
26
引用
收藏
页码：222 / 222
页数：1
相关论文
共 50 条
  • [41] Restoration of histone acetylation ameliorates disease and metabolic abnormalities in a FUS mouse model
    Elisabeth Rossaert
    Eveliina Pollari
    Tom Jaspers
    Lawrence Van Helleputte
    Matthew Jarpe
    Philip Van Damme
    Katrien De Bock
    Matthieu Moisse
    Ludo Van Den Bosch
    Acta Neuropathologica Communications, 7
  • [42] Restoration of histone acetylation ameliorates disease and metabolic abnormalities in a FUS mouse model
    Rossaert, Elisabeth
    Pollari, Eveliina
    Jaspers, Tom
    Van Helleputte, Lawrence
    Jarpe, Matthew
    Van Damme, Philip
    De Bock, Katrien
    Moisse, Matthieu
    Van Den Bosch, Ludo
    ACTA NEUROPATHOLOGICA COMMUNICATIONS, 2019, 7 (1) : 107
  • [43] Nutritional support therapy for liver transplantation in an adult-onset type II citrullinemia patient: a case report
    Du, Yao
    Fu, Yang-Yang
    Yue, Yang
    Han, Bing
    Zhang, Wen-Jie
    Yu, De-Cai
    Bian, Xiao-Jie
    FRONTIERS IN NUTRITION, 2024, 11
  • [44] ACE Reduces Metabolic Abnormalities in a High-Fat Diet Mouse Model
    Lee, Seong-Jong
    Han, Jong-Min
    Lee, Jin-Seok
    Son, Chang-Gue
    Im, Hwi-Jin
    Jo, Hyun-Kyung
    Yoo, Ho-Ryong
    Kim, Yoon-Sik
    Seol, In-Chan
    EVIDENCE-BASED COMPLEMENTARY AND ALTERNATIVE MEDICINE, 2015, 2015
  • [45] Skeletal abnormalities in a mouse model of mucolipidosis II - pathomechanisms and therapeutic strategies
    Kollmann, Katrin
    Pestka, Jan M.
    Karkmann, Kathrin
    Schweizer, Michaela
    Schinke, Thorsten
    Braulke, Thomas
    EUROPEAN JOURNAL OF PEDIATRICS, 2012, 171 (09) : 1428 - 1429
  • [46] Non-integrative and integrative gene-based strategies for the treatment of Citrullinemia type I mouse model
    Lisjak, M.
    Guarnaccia, C.
    Iaconcig, A.
    Zentilin, L.
    Muro, A. F.
    HUMAN GENE THERAPY, 2021, 32 (19-20) : A74 - A74
  • [47] An improved nongenetic mouse model for type 2 diabetes
    Gilbert, Elizabeth Ruth
    Fu, Zhuo
    Liu, Dongmin
    FASEB JOURNAL, 2010, 24
  • [48] Behavioral and histological hallmarks of a mucopolysaccharidosis type IIIA mouse model
    Niederkofler, Vera
    Auer, Ewald
    Amschl, David
    Neddens, Joerg
    Sjostrom, Elisabet Ohlin
    Gustaysson, Susanne
    Huffer-Paier, Birgit
    MOLECULAR GENETICS AND METABOLISM, 2019, 126 (02) : S109 - S109
  • [49] Dopamine depletion attenuates some behavioral abnormalities in a hyperdopaminergic mouse model of bipolar disorder
    van Enkhuizen, Jordy
    Geyer, Mark A.
    Halberstadt, Adam L.
    Zhuang, Xiaoxi
    Young, Jared W.
    JOURNAL OF AFFECTIVE DISORDERS, 2014, 155 : 247 - 254
  • [50] Genetic manipulation of STEP reverses behavioral abnormalities in a fragile X syndrome mouse model
    Goebel-Goody, S. M.
    Wilson-Wallis, E. D.
    Royston, S.
    Tagliatela, S. M.
    Naegele, J. R.
    Lombroso, P. J.
    GENES BRAIN AND BEHAVIOR, 2012, 11 (05) : 586 - 600
12345