Is facial nerve palsy an early manifestation of COVID-19? A literature review

被引：6

作者：

Estakhr, Mehrdad ^{[1
]}

Tabrizi, Reza ^{[2
,3
]}

Ghotbi, Zahra ^{[1
]}

Shahabi, Saeed ^{[4
]}

Habibzadeh, Adrina ^{[2
]}

Bashi, Ali ^{[5
]}

Borhani-Haghighi, Afshin ^{[1
,6
]}

机构：

[1] Shiraz Univ Med Sci, Clin Neurol Res Ctr, Res Tower,Khalili Ave, Shiraz, Iran

[2] Fasa Univ Med Sci, Noncommunicable Dis Res Ctr, Fasa, Iran

[3] Fasa Univ Med Sci, Vali Asr Hosp, Clin Res Dev Unit, Fasa, Iran

[4] Shiraz Univ Med Sci, Inst Hlth, Hlth Policy Res Ctr, Shiraz, Iran

[5] Shiraz Univ Med Sci, Poostchi Ophthalmol Res Ctr, Shiraz, Iran

[6] Clin Neurol Res Ctr, Res Tower,Khalili Ave, Shiraz, Iran

来源：

AMERICAN JOURNAL OF THE MEDICAL SCIENCES | 2022年 / 364卷 / 03期

关键词：

COVID-19; Facial nerve palsy; Peripheral facial nerve palsy; Cranial nerve palsies; SARS-CoV-2; SYNDROME CORONAVIRUS 2; BELLS-PALSY; PATIENT; PREDNISOLONE; ENCEPHALITIS; MYOCARDITIS; MECHANISMS; INFECTION; UPDATE; SPIKE;

D O I：

10.1016/j.amjms.2022.04.010

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

The primary target of SARS-CoV-2 is the respiratory tract; nevertheless, the virus can invade extrapulmonary organs, such as the nervous system. Peripheral facial nerve palsy has been reported in COVID-19 cases as isolated, unilateral, or bilateral in the context of Guillain-Barre syndrome (GBS). In the present study, online databases, including PubMed and Google Scholar, were searched. Studies without focusing on isolated peripheral facial nerve palsy and SARS-CoV-2 were excluded. Finally, 36 patients with facial nerve palsy were included in our study using reverse transcriptase-polymerase chain reaction (RT-PCR) or antibody SARS-CoV-2 positive test. Interestingly, 23 (63.8%) of these patients had no typical history of COVID-19, and facial nerve palsy was their first clinical manifestation. The present study concludes that there is enough evidence to suggest that SARS-CoV-2 infection may present with facial nerve palsy as the initial clinical manifestation.

引用

页码：264 / 273

页数：10

共 64 条

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