Iodobenzene Catalyzed C-H Amination of N-Substituted Amidines Using m-Chloroperbenzoic Acid

被引：132

作者：

Alla, Santhosh Kumar ^{[1
]}

Kumar, Rapolu Kiran ^{[1
]}

Sadhu, Pradeep ^{[1
]}

Punniyamurthy, Tharmalingam ^{[1
]}

机构：

[1] Indian Inst Technol Guwahati, Dept Chem, Gauhati 781039, India

来源：

ORGANIC LETTERS | 2013年 / 15卷 / 06期

关键词：

POLYVALENT IODINE COMPOUNDS; METAL-FREE CONDITIONS; BOND FORMATION; PHENYLIODINE BIS(TRIFLUOROACETATE); INTRAMOLECULAR CYCLIZATION; AMBIENT-TEMPERATURE; OXIDATIVE CYCLIZATION; ARYL BENZIMIDAZOLES; ALKENES; DIAMINATION;

D O I：

10.1021/ol400274f

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The oxidative C-H amination of N ''-aryl-N'-tosyl/N'-methylsulfonylamidines and N,N'-bis(aryl)amidines has been accomplished using iodobenzene as a catalyst to furnish 1,2-disubstituted benzimidazoles in the presence of mCPBA as a terminal oxidant at room temperature. The reaction is general, and the target products can be obtained in moderate to high yields.

引用

页码：1334 / 1337

页数：4

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