Cu-Catalyzed direct cyanation of terminal alkynes with AMBN or AIBN as the cyanation reagent

被引：60

作者：

Rong, Guangwei ^{[1
]}

Mao, Jincheng ^{[1
,2
]}

Zheng, Yang ^{[1
]}

Yao, Ruwei ^{[1
]}

Xu, Xinfang ^{[1
]}

机构：

[1] Soochow Univ, Lab Organ Synth Jiangsu Prov, Coll Chem Chem Engn & Mat Sci, Suzhou 215123, Peoples R China

[2] Southwest Petr Univ, State Key Lab Oil & Gas Reservoir Geol & Exploita, Chengdu 610500, Peoples R China

来源：

CHEMICAL COMMUNICATIONS | 2015年 / 51卷 / 72期

关键词：

H-PHOSPHINE OXIDES; CYANIDE SOURCE; EFFICIENT SYNTHESIS; ARYLBORONIC ACIDS; VINYL SULFONES; ARYL HALIDES; COPPER; PALLADIUM; BONDS; IODIDE;

D O I：

10.1039/c5cc04987c

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A Cu-catalyzed direct cyanation of terminal alkynes was reported with broad substrate generality in moderate to high yield, and AMBN (azobisisoamylonitrile)/AIBN (azobisisobutyronitrile) were used as less toxic and effective cyanating sources in open air. Interestingly, addition products were selectively achieved as the major product under the same conditions in argon.

引用

页码：13822 / 13825

页数：4

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