Ir(bis-NHC)-Catalyzed Direct Conversion of Amines to Alcohols in Aqueous Glycerol

被引：4

作者：

Cheong, Yeon-Joo ^{[1
]}

Lee, Seunghyeon ^{[1
]}

Hwang, Sang Joon ^{[1
]}

Yoon, Woojin ^{[1
]}

Yun, Hoseop ^{[1
]}

Jang, Hye-Young ^{[1
]}

机构：

[1] Ajou Univ, Dept Energy Syst Res, Suwon 16499, South Korea

来源：

EUROPEAN JOURNAL OF ORGANIC CHEMISTRY | 2019年 / 2019卷 / 09期

关键词：

Iridium; Dehydrogenation; Amines; Alcohols; Glycerol; TRANSFER HYDROGENATION; TRANSITION-METAL; N-ALKYLATION; IRIDIUM; REDUCTION; COMPLEXES; DEHYDROGENATION; ALDEHYDES; CATALYSTS; SOLVENT;

D O I：

10.1002/ejoc.201900042

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Sustainable catalytic conversion of amines to alcohols was realized in the presence of iridium catalysts and aqueous glycerol. Iridium catalysts involving bis-N-heterocyclic carbene (bis-NHC) show good reactivity and stability in the conversion of amines into alcohols in aqueous glycerol. The reaction was initiated with the dehydrogenation of amines and followed by hydrolysis and reduction. Iridium catalysts play dual roles in both the dehydrogenation and reduction steps. By employing glycerol as a solvent and hydrogen source, the final reduction was facilitated. The synthesis and characterization of various Ir(bis-NHC) complexes are described along with the catalytic reaction results of the amine into alcohol conversion.

引用

页码：1940 / 1943

页数：4

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