PSGL-1 regulates the extent of TCR-dependent activation in T cells and prevents their suppression by Tregs

被引:0
|
作者
Otero, Dennis C. [1 ]
Takahashi, Amy [1 ]
Chao, Grace [2 ]
Leung, Donmienne [2 ]
Bradley, Linda [1 ]
机构
[1] Sanford Burnham Prebys Med Discovery Inst, San Diego, CA USA
[2] Lilly Biotechnol Ctr, San Diego, CA USA
来源
JOURNAL OF IMMUNOLOGY | 2018年 / 200卷 / 01期
关键词
D O I
暂无
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
引用
收藏
页数:2
相关论文
共 50 条
  • [41] Ezrin-Radixin-Moesin-binding Sequence of PSGL-1 Glycoprotein Regulates Leukocyte Rolling on Selectins and Activation of Extracellular Signal-regulated Kinases
    Spertini, Caroline
    Baisse, Benedicte
    Spertini, Olivier
    JOURNAL OF BIOLOGICAL CHEMISTRY, 2012, 287 (13) : 10693 - 10702
  • [42] The P-selectin and PSGL-1 axis accelerates atherosclerosis via activation of dendritic cells by the TLR4 signaling pathway
    Zhishuai Ye
    Lei Zhong
    Shengnan Zhu
    Yinuo Wang
    Jie Zheng
    Shujing Wang
    Jianing Zhang
    Rongchong Huang
    Cell Death & Disease, 10
  • [43] Proteomic profiling of HIV-1 infection of human CD4+ T cells identifies PSGL-1 as an HIV restriction factor
    Liu, Ying
    Fu, Yajing
    Wang, Qian
    Li, Mushan
    Zhou, Zheng
    Dabbagh, Deemah
    Fu, Chunyan
    Zhang, Hang
    Li, Shuo
    Zhang, Tengjiang
    Gong, Jing
    Kong, Xiaohui
    Zhai, Weiwei
    Su, Jiaming
    Sun, Jianping
    Zhang, Yonghong
    Yu, Xiao-Fang
    Shao, Zhen
    Zhou, Feng
    Wu, Yuntao
    Tan, Xu
    NATURE MICROBIOLOGY, 2019, 4 (05) : 813 - 825
  • [44] Proteomic profiling of HIV-1 infection of human CD4+ T cells identifies PSGL-1 as an HIV restriction factor
    Ying Liu
    Yajing Fu
    Qian Wang
    Mushan Li
    Zheng Zhou
    Deemah Dabbagh
    Chunyan Fu
    Hang Zhang
    Shuo Li
    Tengjiang Zhang
    Jing Gong
    Xiaohui Kong
    Weiwei Zhai
    Jiaming Su
    Jianping Sun
    Yonghong Zhang
    Xiao-Fang Yu
    Zhen Shao
    Feng Zhou
    Yuntao Wu
    Xu Tan
    Nature Microbiology, 2019, 4 : 813 - 825
  • [45] PSGL-1 and fucosyltransferase-VII are involved in the suppressor activity mediated by CD4+CD25+ regulatory T cells
    Rossia, B.
    Bach, S.
    Martinello, M.
    Ottoboni, L.
    Angiari, S.
    McEver, R.
    Lowe, J. B.
    Constantin, G.
    JOURNAL OF NEUROIMMUNOLOGY, 2006, 178 : 106 - 106
  • [46] Generation of memory CD4+T cells after influenza virus infection requires PSGL-1 and selectin binding activity
    Tinoco, Roberto
    Nguyen, Jennifer
    Lin, Melissa
    Bradley, Linda
    JOURNAL OF IMMUNOLOGY, 2013, 190
  • [47] Neutrophils, monocytes, and dendritic cells express the same specialized form of PSGL-1 as do skin-homing memory T cells: Cutaneous lymphocyte antigen
    Kieffer, JD
    Fuhlbrigge, RC
    Armerding, D
    Robert, C
    Ferenczi, K
    Camphausen, RT
    Kupper, TS
    BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2001, 285 (03) : 577 - 587
  • [48] PSGL-1 is an early T cell signaling regulator that drives immunometabolism and terminal differentiation in tumor-specific CD8 T cells.
    Hope, Jennifer L.
    Otero, Dennis C.
    Bae, Eun-ah
    Stairiker, Christopher J.
    Palete, Ashley B.
    Faso, Hannah A.
    de Jong, Petrus
    Powis, Garth
    Bradley, Linda M.
    CANCER IMMUNOLOGY RESEARCH, 2021, 9 (02)
  • [49] Membrane cofactor protein (CD46) induces TCR-dependent NF-kappaB-activation and a distinct cytokine pattern in CD4+ cells
    Kemper, C
    Atkinson, JP
    FASEB JOURNAL, 2002, 16 (04): : A714 - A714
  • [50] NF κB Activation in Embryonic Endothelial Progenitor Cells Enhances Neovascularization Via PSGL-1 Mediated Recruitment: Novel Role for LL37
    Pfosser, Achim
    El-Aouni, Chiraz
    Pfisterer, Iris
    Dietz, Melanie
    Globisch, Franziska
    Stachel, Georg
    Trenkwalder, Teresa
    Pinkenburg, Olaf
    Horstkotte, Jan
    Hinkel, Rabea
    Sperandio, Markus
    Hatzopoulos, Antonis K.
    Boekstegers, Peter
    Bals, Robert
    Kupatt, Christian
    STEM CELLS, 2010, 28 (02) : 376 - 385