Is pneumoconiosis a factor of severity in acute exacerbation of chronic obstructive pulmonary disease?

被引:5
|
作者
Ornek, T. [1 ]
Atalay, F. [1 ]
Erboy, F. [1 ]
Altinsoy, B. [1 ]
Tanriverdi, H. [1 ]
Uygur, F. [1 ]
Tor, M. [1 ]
机构
[1] Bulent Ecevit Univ, Fac Med, Dept Pulm Med, TR-67600 Zonguldak, Turkey
来源
CLINICA TERAPEUTICA | 2013年 / 164卷 / 06期
关键词
coal mining; cost; hospitalization; infection; progressive massive fibrozis; COAL-MINERS; COPD; EPIDEMIOLOGY; FEV1;
D O I
10.7417/CT.2013.1639
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Background and Aim. Although working in a coal mine is a well-known risk factor for chronic obstructive pulmonary disease (COPD), there insufficient data explaining the association between acute exacerbation of COPD (AECOPD) and coal worker pneumoconiosis (CWP). This study aimed to evaluate the features of patients with complicated CWP admitted for AECOPD and whether complicated CWP has any effect on increasing the severity of this disease. Materials and Methods. This study was designed as a retrospective cohort study. A total of 106 hospitalized patients were identified to have CWP. Patients who did not perform spirometry and with simple CWP were excluded. A total of 51 patients with complicated CWP, was included in the study group. Comparison group was selected from the patients with AECOPD without pneumoconiosis. Results. Patients with complicated CWP, when compared to patients without pneumoconiosis, had longer hospitalization times (12.96 +/- 8.49 days, 9.67 +/- 5.21 days respectively, p=0.021), a higher cost of hospitalization ((sic)2029 +/- 2724, (sic)931 +/- 820 respectively, p=0.003), and higher rates of infective microorganisms in respiratory secretions and/or blood cultures (61.3%, 29.6% respectively, p=0.016). We found that significance of high cost was dependent on duration of hospitalization and culture positivity. The most frequently encountered infective microorganism in both groups with complicated CWP and without pneumoconiosis was pseudomonas aeruginosa. Conclusions. Preventive measures for CWP in regions with high prevalence of coal mining have a very important role in the fight against COPD, which has significant morbidity and mortality rates.
引用
收藏
页码:E473 / E477
页数:5
相关论文
共 50 条
  • [31] Pulmonary Embolism in Patients with Acute Exacerbation of Chronic Obstructive Pulmonary Disease
    Cao, Yao-Qian
    Dong, Li-Xia
    Cao, Jie
    CHINESE MEDICAL JOURNAL, 2018, 131 (14) : 1732 - 1737
  • [32] Pulmonary rehabilitation in patients with an acute exacerbation of chronic obstructive pulmonary disease
    Jones, Sarah E.
    Barker, Ruth E.
    Nolan, Claire M.
    Patel, Suhani
    Maddocks, Matthew
    Man, William D. C.
    JOURNAL OF THORACIC DISEASE, 2018, 10 : S1390 - S1399
  • [33] Acute pulmonary embolism in patients with chronic obstructive pulmonary disease exacerbation
    Timofte, Irina L.
    Talanow, Roland
    Kanne, Jeffrey
    Brateanu, Andrei
    CHEST, 2007, 132 (04) : 426S - 427S
  • [34] Acute Pulmonary Embolism in Patients With Chronic Obstructive Pulmonary Disease Exacerbation
    Talanow, R.
    Timofte, I.
    AMERICAN JOURNAL OF ROENTGENOLOGY, 2009, 192 (05)
  • [35] The Effects Of Bronchiectasis Severity On Outcomes Of Chronic Obstructive Pulmonary Disease Exacerbation
    Isikdogan, Zeynep
    Kokturk, Nurdan
    Yapar, Dilek
    Karakus, Pinar
    Kilic, H. Koray
    Erbas, Gonca
    EUROPEAN RESPIRATORY JOURNAL, 2017, 50
  • [36] Circulating fibrocytes are an indicator of severity and exacerbation in chronic obstructive pulmonary disease
    Kaddah, Safy
    Selim, Samah
    Rashed, Laila
    Noaman, Maissa
    EGYPTIAN JOURNAL OF CHEST DISEASES AND TUBERCULOSIS, 2014, 63 (04): : 805 - 813
  • [37] Pharmacoeconomic Analysis of Acute Exacerbation of Chronic Obstructive Pulmonary Disease
    Iqbal, Muhammad Shahid
    Al-Saikhan, Fahad, I
    Ahmed, Nehad J.
    Iqbal, Muhammad Zahid
    JOURNAL OF PHARMACEUTICAL RESEARCH INTERNATIONAL, 2020, 32 (04) : 59 - 66
  • [38] Chronic obstructive pulmonary disease: the clinical management of an acute exacerbation
    Hurst, JR
    Wedzicha, JA
    POSTGRADUATE MEDICAL JOURNAL, 2004, 80 (947) : 497 - 505
  • [39] Acute asthma attack and exacerbation of chronic obstructive pulmonary disease
    Groeben, H.
    Kullmann, H. J.
    NOTFALL & RETTUNGSMEDIZIN, 2011, 14 (01): : 61 - 73
  • [40] Immunodeficiency in Patients with Acute Exacerbation of Chronic Obstructive Pulmonary Disease
    Xie, Sheling
    Wang, Kaifei
    Zhang, Wei
    Xiao, Kun
    Yan, Peng
    Li, Yanqin
    He, Wanxue
    Zhang, Yuhan
    Xie, Lixin
    INFLAMMATION, 2018, 41 (05) : 1582 - 1589