Lymphocyte subset reconstitution in pediatric liver recipients induced with steroid-free rabbit anti-human thymocyte globulin

被引：10

作者：

Talukdar, Anjan ^{[1
,2
]}

AshokKumar, Chethan ^{[1
,2
]}

Farrar, Jennifer ^{[1
,2
]}

Wilson, Patrick ^{[1
,2
]}

Janakiramanan, Arun ^{[1
,2
]}

Tregaskes, Mary ^{[1
,2
]}

Sindhi, Rakesh ^{[1
,2
]}

机构：

[1] Childrens Hosp Pgh, Hillman Ctr Pediat Transplantat, Pediat Transplantat Lab, Pittsburgh, PA USA

[2] Univ Pittsburgh, Pittsburgh, PA USA

来源：

PEDIATRIC TRANSPLANTATION | 2008年 / 12卷 / 07期

关键词：

lymphocyte depleting antibodies; pediatric; liver transplantation; immunosuppression; lymphocyte subsets;

D O I：

10.1111/j.1399-3046.2007.00797.x

中图分类号：

R72 [儿科学];

学科分类号：

100202 ;

摘要：

Multiple measurements of lymphocyte subsets in 91 children treated with steroid-free tacrolimus, and rabbit anti-human thymocyte globulin induction demonstrate early reconstitution of T-cytotoxic cells, and gradual reconstitution of all other subsets, which is complete after one yr. Rejection-prone children demonstrate significantly higher counts of lymphocytes and all subsets prior to liver transplantation, and may exemplify one basis for enhanced baseline immunocompetence.

引用

页码：804 / 808

页数：5