Differential effect of the p53 inducers Nutlin-3 and RITA on cell lines with different p53 status

被引:0
|
作者
Weilbacher, A. [1 ,2 ]
Gutekunst, M. [1 ,2 ]
Oren, M. [3 ]
Aulitzky, W. [4 ]
van der Kuip, H. [1 ,2 ]
机构
[1] Dr Margarete Fischer Bosch Inst Clin Pharmacol, D-7000 Stuttgart, Germany
[2] Univ Tubingen, Stuttgart, Germany
[3] Weizmann Inst Sci, Dept Mol Biol, IL-76100 Rehovot, Israel
[4] Robert Bosch Hosp Stuttgart, Dept Internal Med 2, Stuttgart, Germany
来源
ONKOLOGIE | 2012年 / 35卷
关键词
D O I
暂无
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
引用
收藏
页码:195 / 196
页数:2
相关论文
共 50 条
  • [31] RITA: p53 doesn't resist it
    Jacquemin-Sablon, A
    BULLETIN DU CANCER, 2005, 92 (03) : 217 - 217
  • [32] Nutlin-3: A novel potential therapeutic in p53 wild-type ovarian carcinomas.
    King, Erin Rebecca
    Mullany, Lisa K.
    Richards, JoAnne S.
    Gershenson, David Marc
    Wong, Kwong-Kwok
    JOURNAL OF CLINICAL ONCOLOGY, 2012, 30 (15)
  • [33] A new method for determining the status of p53 in tumor cell lines of different origin
    Gartel, AL
    Feliciano, C
    Tyner, AL
    ONCOLOGY RESEARCH, 2003, 13 (6-10) : 405 - 408
  • [34] Pharmacological activation of the p53 pathway by nutlin-3 exerts anti-tumoral effects in medulloblastomas
    Kuenkele, Annette
    De Preter, Katleen
    Heukamp, Lukas
    Thor, Theresa
    Pajtler, Kristian W.
    Hartmann, Wolfgang
    Mittelbronn, Michel
    Grotzer, Michael A.
    Deubzer, Hedwig E.
    Speleman, Frank
    Schramm, Alexander
    Eggert, Angelika
    Schulte, Johannes H.
    NEURO-ONCOLOGY, 2012, 14 (07) : 859 - 869
  • [35] Synergistic induction of p53 mediated apoptosis by valproic acid and nutlin-3 in acute myeloid leukemia
    McCormack, E.
    Haaland, I.
    Venas, G.
    Forthun, R. B.
    Huseby, S.
    Gausdal, G.
    Knappskog, S.
    Micklem, D. R.
    Lorens, J. B.
    Bruserud, O.
    Gjertsen, B. T.
    LEUKEMIA, 2012, 26 (05) : 910 - 917
  • [36] Human neuroblastoma cells with acquired resistance to the p53 activator RITA retain functional p53 and sensitivity to other p53 activating agents
    Michaelis, M.
    Rothweiler, F.
    Agha, B.
    Barth, S.
    Voges, Y.
    Loeschmann, N.
    von Deimling, A.
    Breitling, R.
    Doerr, H. Wilhelm
    Roedel, F.
    Speidel, D.
    Cinatl, J., Jr.
    CELL DEATH & DISEASE, 2012, 3 : e294 - e294
  • [37] Human neuroblastoma cells with acquired resistance to the p53 activator RITA retain functional p53 and sensitivity to other p53 activating agents
    M Michaelis
    F Rothweiler
    B Agha
    S Barth
    Y Voges
    N Löschmann
    A von Deimling
    R Breitling
    H Wilhelm Doerr
    F Rödel
    D Speidel
    J Cinatl
    Cell Death & Disease, 2012, 3 : e294 - e294
  • [38] The combined effect of neutron irradiation and temozolomide on glioblastoma cell lines with different MGMT and P53 status
    Kinashi, Yuko
    Ikawa, Tomoyuki
    Takahashi, Sentaro
    APPLIED RADIATION AND ISOTOPES, 2020, 163 (163)
  • [39] Restoration of p53 functions suppresses tumor growth of pancreatic cells with different p53 status
    Taghavi, Marzieh H. S.
    Davoodi, Jarnshid
    CANCER BIOTHERAPY AND RADIOPHARMACEUTICALS, 2007, 22 (03) : 322 - 332
  • [40] Living with p53, dying of p53
    Aylon, Yael
    Oren, Moshe
    CELL, 2007, 130 (04) : 597 - 600