Expeditious synthetic approach and photophysical properties of fluorescent benzimidazo[1,2-d]dibenzo[b,f][1,4]diazepine derivatives

被引：3

作者：

Mitra, Sudipta ^{[1
]}

Chattopadhyay, Nitin ^{[2
]}

Chattopadhyay, Partha ^{[1
]}

机构：

[1] Indian Inst Chem Biol, CSIR, Div Chem, Kolkata 700032, India

[2] Jadavpur Univ, Dept Chem, Kolkata 700032, India

来源：

RSC ADVANCES | 2013年 / 3卷 / 06期

关键词：

BIOLOGICAL EVALUATION; ANTI-HIV-1; ACTIVITY; EFFICIENT SYNTHESIS; PALLADIUM; ELECTROLUMINESCENCE; ARYL; PERSPECTIVES; ANALOGS;

D O I：

10.1039/c2ra22527a

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A short and efficient synthetic route to novel benzimidazo[1,2-d]dibenzo[b,f][1,4]diazepines has been developed using a copper catalyzed intramolecular Ullmann type C-N bond forming reaction as a key step. Copper iodide and 1,10-phenanthroline furnished the desired compounds in good yield. The products are intensely fluorescent with appreciably long lifetimes. Looking at their prospective use as markers for biomacromolecules and in biochemical analysis, we have explored the photophysical properties of these compounds. The spectrophotometric and spectrofluorometric studies reveal that while the absorbance maxima of the compounds are in the UV region, the emission maxima fall in the visible (blue-green) region.

引用

页码：1862 / 1870

页数：9

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