Cellulose Sulfuric Acid as an Eco-Friendly Catalyst for Novel Synthesis of Pyrido[2,3-d][1,2,4]triazolo[4,3-a]pyrimidin-5-ones

被引：14

作者：

Gomha, Sobhi M. ^{[1
]}

Riyadh, Sayed M. ^{[1
,2
]}

机构：

[1] Cairo Univ, Fac Sci, Dept Chem, Giza 12613, Egypt

[2] Taibah Univ, Fac Sci, Dept Chem, Almadinah Almunawrah 30002, Saudi Arabia

来源：

JOURNAL OF THE BRAZILIAN CHEMICAL SOCIETY | 2015年 / 26卷 / 05期

关键词：

cellulose sulfuric acid; chalcone; annelated heterocyclic ring system; POT 3-COMPONENT SYNTHESIS; DERIVATIVES; AGENTS;

D O I：

10.5935/0103-5053.20150052

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A novel synthesis of a series of pyrido[2,3-d][1,2,4]triazolo[4,3-a]pyrimidin-5-ones has been developed from reactions of 1-(5-methyl-1-phenyl-1H-pyrazol-4-yl)-3-arylprop-2-en-1-ones and 7-amino-1,3-disubstituted[1,2,4]triazolo[4,3-a]pyrimidin-5(1H)-ones in dioxane under thermal conditions, using cellulose sulfuric acid as an eco-friendly acid catalyst. The reaction mechanism was proposed and the structures of the newly synthesized compounds were established on the basis of spectral data (mass spectrometry, infrared, H-1 and C-13 nuclear magnetic resonance) and elemental analyses.

引用

页码：916 / 923

页数：8

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