Cellulose Sulfuric Acid as an Eco-Friendly Catalyst for Novel Synthesis of Pyrido[2,3-d][1,2,4]triazolo[4,3-a]pyrimidin-5-ones

被引：14
|
作者：
Gomha, Sobhi M. [1 ]
Riyadh, Sayed M. [1 ,2 ]
机构：
[1] Cairo Univ, Fac Sci, Dept Chem, Giza 12613, Egypt
[2] Taibah Univ, Fac Sci, Dept Chem, Almadinah Almunawrah 30002, Saudi Arabia
来源：
JOURNAL OF THE BRAZILIAN CHEMICAL SOCIETY | 2015年 / 26卷 / 05期
关键词：
cellulose sulfuric acid; chalcone; annelated heterocyclic ring system; POT 3-COMPONENT SYNTHESIS; DERIVATIVES; AGENTS;
D O I：
10.5935/0103-5053.20150052
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
A novel synthesis of a series of pyrido[2,3-d][1,2,4]triazolo[4,3-a]pyrimidin-5-ones has been developed from reactions of 1-(5-methyl-1-phenyl-1H-pyrazol-4-yl)-3-arylprop-2-en-1-ones and 7-amino-1,3-disubstituted[1,2,4]triazolo[4,3-a]pyrimidin-5(1H)-ones in dioxane under thermal conditions, using cellulose sulfuric acid as an eco-friendly acid catalyst. The reaction mechanism was proposed and the structures of the newly synthesized compounds were established on the basis of spectral data (mass spectrometry, infrared, H-1 and C-13 nuclear magnetic resonance) and elemental analyses.
引用
收藏
页码：916 / 923
页数：8
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