Lipopolysaccharide recognition, CD14, and lipopolysaccharide receptors

被引：125

作者：

Ingalls, RR ^{[1
]}

Heine, H ^{[1
]}

Lien, E ^{[1
]}

Yoshimura, A ^{[1
]}

Golenbock, D ^{[1
]}

机构：

[1] Boston Univ, Med Ctr, Sch Med, Maxwell Finland Lab Infect Dis, Boston, MA 02118 USA

来源：

INFECTIOUS DISEASE CLINICS OF NORTH AMERICA | 1999年 / 13卷 / 02期

关键词：

D O I：

10.1016/S0891-5520(05)70078-7

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

The ability of a host to sense invasion by a pathogenic organism, and to respond appropriately to control infection, is paramount to survival. To that end, an array of receptors and binding proteins has evolved as part of the innate immune system to detect Gram-negative bacteria. This article reviews the role of CD14, other LPS binding proteins, and the Toll family of receptors in the innate recognition of bacterial lipopolysaccharide.

引用

页码：341 / +

页数：14

共 50 条

[21] Kupffer cells contain a functional CD14 lipopolysaccharide receptor [J].

Ikejima, K ;

Enomoto, N ;

Seabra, V ;

Ikejima, A ;

Watanabe, S ;

Sato, N ;

Brenner, DA ;

Thurman, RG .

CELLS OF THE HEPATIC SINUSOID, VOL 7, 1999, :232-234

[22] Pronase destroys the lipopolysaccharide receptor CD14 on Kupffer cells [J].

Ikejima, K ;

Enomoto, N ;

Seabra, V ;

Ikejima, A ;

Brenner, DA ;

Thurman, RG .

AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY, 1999, 276 (03) :G591-G598

[23] CD14 expression and binding of lipopolysaccharide to alveolar macrophages and monocytes [J].

Haugen, TS ;

Nakstad, B ;

Skjonsberg, OH ;

Lyberg, T .

INFLAMMATION, 1998, 22 (05) :521-532

[24] A CD14 domain with lipopolysaccharide-binding and -neutralizing activity [J].

Voss, S ;

Welte, S ;

Fotin-Mleczek, M ;

Fischer, R ;

Ulmer, AJ ;

Jung, G ;

Wiesmuller, KH ;

Brock, R .

CHEMBIOCHEM, 2006, 7 (02) :275-286

[25] Crystal structure of CD14 and its implications for lipopolysaccharide signaling [J].

Kim, JI ;

Lee, CJ ;

Jin, MS ;

Lee, CH ;

Paik, SG ;

Lee, H ;

Lee, JO .

JOURNAL OF BIOLOGICAL CHEMISTRY, 2005, 280 (12) :11347-11351

[26] Stimulation of macrophages and neutrophils by complexes of lipopolysaccharide and soluble CD14 [J].

Hailman, E ;

Vasselon, T ;

Kelley, M ;

Busse, LA ;

Hu, MCT ;

Lichenstein, HS ;

Detmers, PA ;

Wright, SD .

JOURNAL OF IMMUNOLOGY, 1996, 156 (11) :4384-4390

[27] Soluble CD14 activates monocytic cells independently of lipopolysaccharide [J].

Landmann, R ;

Link, S ;

Sansano, S ;

Rajacic, Z ;

Zimmerli, W .

INFECTION AND IMMUNITY, 1998, 66 (05) :2264-2271

[28] TRANSGENIC MICE EXPRESSING HUMAN CD14 ARE HYPERSENSITIVE TO LIPOPOLYSACCHARIDE [J].

FERRERO, E ;

JIAO, D ;

TSUBERI, BZ ;

TESIO, L ;

RONG, GW ;

HAZIOT, A ;

GOYERT, SM .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1993, 90 (06) :2380-2384

[29] CD14 dependent and independent signaling of lipopolysaccharide in mouse hepatocytes [J].

Scott, MJ ;

Billiar, TR .

FASEB JOURNAL, 2005, 19 (04) :A400-A400

[30] SEPTIN - A FACTOR IN PLASMA THAT OPSONIZES LIPOPOLYSACCHARIDE-BEARING PARTICLES FOR RECOGNITION BY CD14 ON PHAGOCYTES [J].

WRIGHT, SD ;

RAMOS, RA ;

PATEL, M ;

MILLER, DS .

JOURNAL OF EXPERIMENTAL MEDICINE, 1992, 176 (03) :719-727

← 1 2 3 4 5 →